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Suggest Treatment For Mild Perifollicullar Fibrosis And Chronic Inflammation
Question: Follow up to my diagnosed condition: Mild perifollicullar fibrosis and chronic inflammation
Brief Answer:
You may use tacrolimus ointment
Detailed Answer:
Hi. Welcome back.
What you have now is a burnt out disease as also revealed in biopsy which says perifollicular fibrosis (i.e hair follicle are permanently destroyed).
Discoloration (hypopigmentation as well as hyperpigmentation) is a part of this disease process and is post-inflammatory. It may persist for years.
Pigmentary changes would be slow to respond.
Since you are concerned about the hypopigmented patches therefore I suggest that you may use tacrolimus 0.1% ointment, twice daily, specifically for these lighter patches/ area. Rub it in gently.
Regards
You may use tacrolimus ointment
Detailed Answer:
Hi. Welcome back.
What you have now is a burnt out disease as also revealed in biopsy which says perifollicular fibrosis (i.e hair follicle are permanently destroyed).
Discoloration (hypopigmentation as well as hyperpigmentation) is a part of this disease process and is post-inflammatory. It may persist for years.
Pigmentary changes would be slow to respond.
Since you are concerned about the hypopigmented patches therefore I suggest that you may use tacrolimus 0.1% ointment, twice daily, specifically for these lighter patches/ area. Rub it in gently.
Regards
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
in regards to the post inflammatory issue, what do you recommend to arrest this?
Also I have the read on the side effects of tacrolimus ointments (i.e. skin cancer possibilities), what are your thoughts? any other alternatives?
Also I have the read on the side effects of tacrolimus ointments (i.e. skin cancer possibilities), what are your thoughts? any other alternatives?
Brief Answer:
Topical tacrolimus is safe.
Detailed Answer:
Hi.
Post-inflammatory hypopigmentation is part of the disease process. In your case since it is a burnt out disease (i.e already stopped progressing) therefore I don't see the post-inflammatory changes progressing any further than this.
Topical tacrolimus is safe. There is no causal relationship that has been established between topical tacrolimus and malignancy.
Systemic use of tacrolimus e.g in organ transplant recipients is associated with immunosuppression and therefore risk of cancer but for topical use on a limited area this is not a worry.
Therefore you may safely use tacrolimus over the hypopigmented patches, twice daily.
Regards
Topical tacrolimus is safe.
Detailed Answer:
Hi.
Post-inflammatory hypopigmentation is part of the disease process. In your case since it is a burnt out disease (i.e already stopped progressing) therefore I don't see the post-inflammatory changes progressing any further than this.
Topical tacrolimus is safe. There is no causal relationship that has been established between topical tacrolimus and malignancy.
Systemic use of tacrolimus e.g in organ transplant recipients is associated with immunosuppression and therefore risk of cancer but for topical use on a limited area this is not a worry.
Therefore you may safely use tacrolimus over the hypopigmented patches, twice daily.
Regards
Note: Hope the answers resolves your concerns, however for further guidance of skin related queries consult our Dermatologist.Click here to book a consultation
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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