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Suggest Treatment For Monoclonal Kappa Chain Myeloma

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Posted on Wed, 3 Jun 2015
Question: my lambda light chain , free is 1.47 low, Free K/L ration is 6.78 high, immunofixation, 24 hr urine is abnormal, protein random urine is 59 high, IgM, quant 44 low, Paraprotein screen, misc. 0.3 abnormal, MO% 8.8 high, MCHC 32.2 low, what does all of this mean. If I was your patience what would you recommend for me.
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Answered by Dr. Hardik Sanghvi (1 hour later)
Brief Answer:
You have monoclonal kappa chain myeloma.

Detailed Answer:
Hi,

I have gone through your question. I can understand your concern.

As I understand you have kappa lamda (K/L) ratio 6.78. It is very high. Normal kappa to lamda ratio is 0.26 to 1.65. If ratio less than 0.26 then it is called lamda chain myeloma and ratio more than 1.65 is suggestive of monoclonal kappa chain myeloma. This monoclonal proliferation has high risk of developing multiple myeloma.

Preventive treatment to prevent multiple myeloma has many side effects. So its better to go for follow up. Therefore if you were my patient then I would only advice regular follow up every six months. Right now no treatment is required.

Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic.
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now
Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Hardik Sanghvi

Hematologist

Practicing since :2008

Answered : 7043 Questions

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Suggest Treatment For Monoclonal Kappa Chain Myeloma

Brief Answer: You have monoclonal kappa chain myeloma. Detailed Answer: Hi, I have gone through your question. I can understand your concern. As I understand you have kappa lamda (K/L) ratio 6.78. It is very high. Normal kappa to lamda ratio is 0.26 to 1.65. If ratio less than 0.26 then it is called lamda chain myeloma and ratio more than 1.65 is suggestive of monoclonal kappa chain myeloma. This monoclonal proliferation has high risk of developing multiple myeloma. Preventive treatment to prevent multiple myeloma has many side effects. So its better to go for follow up. Therefore if you were my patient then I would only advice regular follow up every six months. Right now no treatment is required. Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic.