Brief Answer:
As detailed below.

Detailed Answer:
Hi.
Thanks for your query, proper history and clear pictures.
Understood your concerns about your Mother.
Noted the history about back surgeries, lots of medicines she is taking, skin lesions for over 5 years, all over the body, since visit to Rotan. Sores beginning as slight lumps with yellowish color and then persist into craters as depicted in pictures.
My thoughts after careful study of the history and the pictures you have provided:
- The possibility of miniature insects or unknown organisms causing such a problem can be considered since these are known to occur in some patients and very difficult to pin-point the causative organism as well as to find the effective treatment hence the treatment is always on assumption basis and helped by the investigations and guidance of the Dermatologist/ Parasitologist/ Infection Disease Specialist
I would advise you the following in such a case:
Cleaning the wounds with Hydrogen peroxide and application of Liquid povidone iodine the the affected area and the skin around. This may help to reduce the infective agent load and possible curative management.
Pus/Discharge: for gram staining, AFB staining, finding the causative organisms, culture and sensitivity.
Biopsy from an active lesion.
Therapeutic trial with antibiotics, Metronidazole orally.
Multivitamins and Vitamin D and A supplements after blood tests as these are vital for integrity/strength of the skin and mucous membrane.
Consultation of a Dermatologist/ Parasitologist/ Infectious Disease Specialist may help in addition.
Control of any medical disease is also needed if present, for example diabetes or so.
Paring of nails is a simple method of control of spread.

I hope this answer helps your Mother.
Please get all these things done and give me feedback, fresh photos, opinions of Specialists, the progression as these will help me to assist you/Mother better till she is cured.
Let us see the progress.

All the best for her recovery.

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Brief Answer:
as explained in details.

Detailed Answer:
Thanks for your appreciation and feedback.
Well, we see such patients not too often but from time to time and do treat too.
We have many from farmer community that are affected.
I myself had such an affection when we had rain-water lodged in house and street in 2006, the lesions appeared after 2 weeks of exposure exactly at the level of calf in encircling fashion. Treated with Liquid Povidone Iodine/ Betadine and Doxycyclin orally.
These are the cases wherein old, abandoned antibiotics may work.
As explained above, discharge from the lesions before they are open- that is in the yellow stage for staining, culture and sensitivity.
Biopsy from the edge of the lesion helps sometimes in diagnosis.

Part of the treatment be as already explained above.
Cleaning the wounds with Hydrogen peroxide and application of Liquid povidone iodine the the affected area and the skin around. This may help to reduce the infective agent load and possible curative management.
Pus/Discharge: for gram staining, AFB staining, finding the causative organisms, culture and sensitivity.
Biopsy from an active lesion.
Therapeutic trial with antibiotics, Metronidazole orally.
Multivitamins and Vitamin D and A supplements after blood tests as these are vital for integrity/strength of the skin and mucous membrane.
Consultation of a Dermatologist/ Parasitologist/ Infectious Disease Specialist may help in addition.
Control of any medical disease is also needed if present, for example diabetes or so.
Paring of nails is a simple method of control of spread.

Please inquire in Pharmacy about availability of Papain powder made from Papaya/ Papacarie, a gel/ Green- unripe papaya in market.

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