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Suggest Treatment For Thyroid Hormone Resistance
Question: My 30 year old daughter has thyroid hormone resistance. She does not convert T4 to T3. She currently takes 150mcg synthetic cytomel and still struggles with hypothyroid symptoms from time to time. Her TSH is completely suppressed. She has had prolonged menstrual cycles since her first period. If we even try to back her thyroid hormone down or introduce T4, she begins to bleed. She is having difficulty getting pregnant. We are using progesterone after ovulation until her period starts but she is still not able to get pregnant. She gets the LH rise each month but not pregnant. What can we do to help the situation? She is not over weight. She eats a very healthy diet (no sugar at all) She has been on prenatal vitamins for over 7 years. Any support and guidance would be appreciated.
Brief Answer:
Thyroid
Detailed Answer:
Sorry to learn about your daughter's thyroid problem.
As you may already very well know, thyroid hormone resistance is a rare condition.
Only a handful of endocrinologists in US have experience and expertise in diagnosing and managing it 100% correctly.
I am aware of Dr XXXXXXX Yen at Johns XXXXXXX in XXXXXXX Maryland as one of them.
Even if you cannot locate him in particular, the best chance for your daughters' thyroid problem is to seek consultation at a reputed academic medical center such as the NIH in Bethesda, Maryland or Mayo clinic 9Rochester, Minnesota or couple more locations) where rare conditions are dealt with in far greater volumes that those seen by the average endocrinologist in private practice such as myself.
They will explicate the intricacies, for example which type of thyroid hormone resistance she has in the first place. General and Peripheral are two examples. These are complex issues.
Thyroid
Detailed Answer:
Sorry to learn about your daughter's thyroid problem.
As you may already very well know, thyroid hormone resistance is a rare condition.
Only a handful of endocrinologists in US have experience and expertise in diagnosing and managing it 100% correctly.
I am aware of Dr XXXXXXX Yen at Johns XXXXXXX in XXXXXXX Maryland as one of them.
Even if you cannot locate him in particular, the best chance for your daughters' thyroid problem is to seek consultation at a reputed academic medical center such as the NIH in Bethesda, Maryland or Mayo clinic 9Rochester, Minnesota or couple more locations) where rare conditions are dealt with in far greater volumes that those seen by the average endocrinologist in private practice such as myself.
They will explicate the intricacies, for example which type of thyroid hormone resistance she has in the first place. General and Peripheral are two examples. These are complex issues.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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