Brief Answer:
Vitiligo treatment
Detailed Answer:
Hello and Welcome to healthcaremagic
I am Dr. Kakkar. I have gone through your concern and understood it.
Vitiligo is a condition characterized by the autoimmune destruction of melanocytes, resulting in loss of pigmentation. In vitiligo, there is a partial or total destruction of melanocytes, initially only of the
epidermis and later even of the hair follicle, which acts as a reservoir for providing melanocytes during repigmentation.
Vitiligo can be of various types depending on the distribution of lesions: 3 types commonly seen are:
-Focal Vitiligo
-Segmental Vitiligo
-Generalised Vitiligo
Judging from the distribution of the lesions, you seem to be having a generalised type of vitiligo, where patches are widespread and symmterical involvement is common (e.g Bilateral arms, bilateral legs, trunk and torso etc)
Medical therapies are the primary treatment for vitiligo. To enumerate them, they can be divided into topical and oral.
--Topicals e.g Topical
steroids, Topical immunomodulators like Tacrolimus, Topical PUVA (Melanocyl lotion)etc
--Oral e.g Oral PUVA(Melanocyl tablets), NB-UVB
phototherapy, Oral steroids etc.
For generalised vitiligo, as seems the case here, Phototherapy remains the mainstay of treatment e.g NB-UVB and PUVA. NB-UVB is the most preferred form of therapy for patients with generalised vitiligo since it is safe, effective, well tolerable and gives long lasting results/re-pigmentation. It can also be given in children and even pregnant ladies because of its safety profile.
Disadvantages with NB-UVB Phototherapy are:
-It requires to be adnministered 3 times in a week for several weeks.
-It is expensive.
Topical are an adjuvant to systemic treatment and include topical steroids and topical immunomodulators like tacrolimus. They accelerate the response to systemic therapy.
At last, I would want to say that Vitiligo is a remitting and relapsing condition and no one can predict the future course of the disease. Treatment is directed at repigmenting the already existing patches with the most appropriate modality suitable for the particular type of vitiligo.
Sometimes it responds very well at certain body sites like trunk, limbs and face but remains resistant OR responds slowly at certain body areas like lips(perioral), fingers, palms, soles and
scalp etc
The duration of phototherapy varies according to the severity/extent of vitiligo. There is no fixed duration for phototherapy. It is individualized for each patient. The duration can vary from a few weeks to a few months depending on the response. Phototherapy can be continued even for maintenance after a satisfactory response. Topical therapy is only for the existing patches of vitiligo and the duration depends on the response.
The decision to stop treatment is made usually after satisfactory repigmentation of the patches is achieved OR most of the patches is achieved. For a few resistant patches of vitiligo that remain, Phototherapy can be continued with a topical
psoralen Or hand help NB-UVB phototherapy unit, rather than exposing the whole body. Topical therapy is usually continued along with phototherapy.
The surrounding dark skin is usually a side effect of phototherapy and fades away gradually in a few weeks, once the treatment is over. This manifest as
tanning and is only up to a limit. This is not much of a concern usually with NB-UVB than it is with PUVA
Hope this answers your query
regards