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Suggest Ways To Lower Elevated GGT Level In Blood While Having HCV Genotype 1a
Question: I have an elevated ggt of 257 Ld of 224 ast of 45 and alt of 53, Yes I have Hep C geno 1a, and have been through interferon and ribraviron treatment once ( for three months non-responding) and then interferon, ribraviron and brocepravir treatment as well ( 11 months responded then tested positive once treatment ended) this year in april. My latest test of elevated ggt etc are from 26.10.2015. How worried should I be and what can I do to help lower my levels.
Kindest Regards
xxxxxxxxxxxxxx
Kindest Regards
xxxxxxxxxxxxxx
Brief Answer:
It requires certain other tests as well as clinical correlation.
Detailed Answer:
Thanks for asking on HealthcareMagic.
Hepatitis C leads to chronic hepatitis which can lead to cirrhosis/fibrosis of the liver. Hence, apart from the parameters of liver function (like AST, GGT), parameters like Viral load need to be measured. A raised LD level indicates tissue turnover and destruction whereas a raised GGT denotes viral activity. There are Noninvasive Markers of Fibrosis which need to be calculated and they include the AST-to-platelet ratio index (APRI), a blood test that uses a combination of six serum markers known as the FibroTest (or HCV-FibroSURE), and a blood test combination of three markers (tissue inhibitory metalloprotease-1, hyaluronic acid, and alfa-2 macroglobulin) referred to as the (FIBROSpect II), Forns Fibrosis Index (age, platelet count, GGT, and cholesterol), and FIB-4 (platelets, ALT, AST, and age).
With modern therapies including interferons very good treatment responses are expected and you should talk to your treating physician whether he feels change in treatment regimen to be required.
Regards
It requires certain other tests as well as clinical correlation.
Detailed Answer:
Thanks for asking on HealthcareMagic.
Hepatitis C leads to chronic hepatitis which can lead to cirrhosis/fibrosis of the liver. Hence, apart from the parameters of liver function (like AST, GGT), parameters like Viral load need to be measured. A raised LD level indicates tissue turnover and destruction whereas a raised GGT denotes viral activity. There are Noninvasive Markers of Fibrosis which need to be calculated and they include the AST-to-platelet ratio index (APRI), a blood test that uses a combination of six serum markers known as the FibroTest (or HCV-FibroSURE), and a blood test combination of three markers (tissue inhibitory metalloprotease-1, hyaluronic acid, and alfa-2 macroglobulin) referred to as the (FIBROSpect II), Forns Fibrosis Index (age, platelet count, GGT, and cholesterol), and FIB-4 (platelets, ALT, AST, and age).
With modern therapies including interferons very good treatment responses are expected and you should talk to your treating physician whether he feels change in treatment regimen to be required.
Regards
Above answer was peer-reviewed by :
Dr. Yogesh D
Thank you for your response. I do need take more attention to dietary specifics with this disease as this does have an impact on liver disease. Here in Australia we are hoping the government will pass the next treatment regime which is a drug called Sovaldi. Third time lucky I hope.
Kindest regards XXXXXXX
Kindest regards XXXXXXX
Brief Answer:
Glad to help
Detailed Answer:
Dietary restrictions are important.
Best of luck with Sovaldi (sofosbuvir).
Let me know if I could help further.
Regards
Glad to help
Detailed Answer:
Dietary restrictions are important.
Best of luck with Sovaldi (sofosbuvir).
Let me know if I could help further.
Regards
Note: For further follow up on digestive issues share your reports here and Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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