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What Are Potential For HCV Transmission By Schistosoma Parasites?
Question: Hello
I have question about Schistosoma
1. There is publication that discus possibility of HCV transmission by Schistosoma
Screening of schistosome DNA by PCR, lead to the
detection of sequences similar to HCV. PCR products were obtained when adult worms genomic DNA were used as templates while
no PCR products were amplified from S. mansoni λZAPII cDNA library pool. The resulting PCR products were sequenced and compared
with the other closely related HCV sequence database at the website < http://hcv.lanl.gov>. Conclusions: This work demonstrates the
existence of HCV and its replication in the genomic DNA of S. mansoni. In addition, it highlights the fact that the parasite can carry the
virus genome and therefore, is considered as a nonhuman vector for the transmission of HCV infections.
https://ccij-online.org/storage/files/article/ccij-ssasu5m9hno-383/ClinCancerInvestigJ_2015_4_3_318_151937.pdf
I don't think that it is true - because there no science evidence - and no conclusion from World Health Organization and CDC
And in publication it is said HVC in Schistosoma vary from low as 1 % to 50% - as this number is so different it show that it is not true
Similarly, published data about HCV and schistosomiasis co infection is scanty where only 16 articles could fulfill our criteria. Prevalence rates of HCV infection with wide variations as low as 1% and as high as 50% among patients with schistosomiasis, were reported in different countries
There have been study that took samples from schistosome rectal snip and they where positive for HCV DNA - but it does not prove evidence of HCV transmission as some fragments of HCV DNA does not prove HCV transmission
ISH revealed HCV RNA in 26.3% of schistosomal ova-positive rectal snips
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1492-7535.2005.1121an.x
What is your comment -
I dont think that Schistosoma could transmit HCV as it would be written in all literature - with lot of evidence
and in WHO and CDC would confirm that Schistosoma could transmit HCV
Thank you
I have question about Schistosoma
1. There is publication that discus possibility of HCV transmission by Schistosoma
Screening of schistosome DNA by PCR, lead to the
detection of sequences similar to HCV. PCR products were obtained when adult worms genomic DNA were used as templates while
no PCR products were amplified from S. mansoni λZAPII cDNA library pool. The resulting PCR products were sequenced and compared
with the other closely related HCV sequence database at the website < http://hcv.lanl.gov>. Conclusions: This work demonstrates the
existence of HCV and its replication in the genomic DNA of S. mansoni. In addition, it highlights the fact that the parasite can carry the
virus genome and therefore, is considered as a nonhuman vector for the transmission of HCV infections.
https://ccij-online.org/storage/files/article/ccij-ssasu5m9hno-383/ClinCancerInvestigJ_2015_4_3_318_151937.pdf
I don't think that it is true - because there no science evidence - and no conclusion from World Health Organization and CDC
And in publication it is said HVC in Schistosoma vary from low as 1 % to 50% - as this number is so different it show that it is not true
Similarly, published data about HCV and schistosomiasis co infection is scanty where only 16 articles could fulfill our criteria. Prevalence rates of HCV infection with wide variations as low as 1% and as high as 50% among patients with schistosomiasis, were reported in different countries
There have been study that took samples from schistosome rectal snip and they where positive for HCV DNA - but it does not prove evidence of HCV transmission as some fragments of HCV DNA does not prove HCV transmission
ISH revealed HCV RNA in 26.3% of schistosomal ova-positive rectal snips
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1492-7535.2005.1121an.x
What is your comment -
I dont think that Schistosoma could transmit HCV as it would be written in all literature - with lot of evidence
and in WHO and CDC would confirm that Schistosoma could transmit HCV
Thank you
Brief Answer:
Please see detailed answer
Detailed Answer:
Hi,
The publications you mentioned describe studies that have explored the potential for HCV transmission by Schistosoma parasites. These studies used PCR (Polymerase Chain Reaction) techniques to detect HCV-like sequences in Schistosoma DNA. However, as you rightly pointed out, the prevalence rates and results of these studies have shown a wide variation, and the evidence is not entirely conclusive.
Additional research and evidence are needed to establish this link conclusively.
There is not a definite consensus from organizations like the World Health Organization (WHO) or the Centers for Disease Control and Prevention (CDC) regarding Schistosoma's role in HCV transmission.
So there is not much evidence yet to support or deny this type of transmission, and in my view I do not support such possibility.
I Hope Your Query is clear now.
Thank You
Please see detailed answer
Detailed Answer:
Hi,
The publications you mentioned describe studies that have explored the potential for HCV transmission by Schistosoma parasites. These studies used PCR (Polymerase Chain Reaction) techniques to detect HCV-like sequences in Schistosoma DNA. However, as you rightly pointed out, the prevalence rates and results of these studies have shown a wide variation, and the evidence is not entirely conclusive.
Additional research and evidence are needed to establish this link conclusively.
There is not a definite consensus from organizations like the World Health Organization (WHO) or the Centers for Disease Control and Prevention (CDC) regarding Schistosoma's role in HCV transmission.
So there is not much evidence yet to support or deny this type of transmission, and in my view I do not support such possibility.
I Hope Your Query is clear now.
Thank You
Above answer was peer-reviewed by :
Dr. Kampana
Thank you
I also don't support theory that Schistosome could transmit HCV - to my mind it is not logic
Thank you
I also don't support theory that Schistosome could transmit HCV - to my mind it is not logic
Thank you
Brief Answer:
Please see detailed answer
Detailed Answer:
Hi,
Yes, you are right,
I agree.
I Hope Your Query is clear now.
Thank You
Please see detailed answer
Detailed Answer:
Hi,
Yes, you are right,
I agree.
I Hope Your Query is clear now.
Thank You
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Above answer was peer-reviewed by :
Dr. Raju A.T
Answered by
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