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What Are The Chances Of Recovery From HCV Infection?
Question: my wife is 34 years old and she is HCV patient,
her viral load 477000 ml
log value:- 5.68
HCV genotype 3
Liver fuction test report
http://scr.hu/33n0/la7ko
1) i wanted to know if she should start treatment based on interferon and ribavirin for 24 weeks
or she can wait for new treatment sovalidi , which will be available within 1 year
2) what are chance of getting rid of virus if we choose the treatment based on
interferon and ribavirin 24 weeks
3) if we choose interferon and ribavirin treatment . can she become pregenant once treatment is finished , are there any side effects on her fertily or fetus
her viral load 477000 ml
log value:- 5.68
HCV genotype 3
Liver fuction test report
http://scr.hu/33n0/la7ko
1) i wanted to know if she should start treatment based on interferon and ribavirin for 24 weeks
or she can wait for new treatment sovalidi , which will be available within 1 year
2) what are chance of getting rid of virus if we choose the treatment based on
interferon and ribavirin 24 weeks
3) if we choose interferon and ribavirin treatment . can she become pregenant once treatment is finished , are there any side effects on her fertily or fetus
Brief Answer:
Treatment indicated
Detailed Answer:
Hello, I have seen okk the details you have provided.
1. You can probably wait for a year under normal circumstances. But your wife's SGOT and SGPT are 1.5 times and two times the upper limit. This suggests that their is on going liver damage. Interferon and ribavarin can be initiated at this point. In case you decide to wait I would suggest a liver biopsy. If this shows minimal fibrosis and Inflammation you can wait for sobo to become available.
2 In case you use ribavarin and interferon the chances of becoming negative are approximately 80 to 90 percent ( this is if viral load becomes undetectable at 4 and 12 weeks).
3. In case you choose interferon and ribavarin , pregnancy should be avoided for 6 months after completion of the treatment as interferon can cause abortions and ribavarin is associaed with teratogenicity.
A six month break should be safe
Hope this helps
Do get back in case you have further queries
Regards
Dr Samir Patil
Treatment indicated
Detailed Answer:
Hello, I have seen okk the details you have provided.
1. You can probably wait for a year under normal circumstances. But your wife's SGOT and SGPT are 1.5 times and two times the upper limit. This suggests that their is on going liver damage. Interferon and ribavarin can be initiated at this point. In case you decide to wait I would suggest a liver biopsy. If this shows minimal fibrosis and Inflammation you can wait for sobo to become available.
2 In case you use ribavarin and interferon the chances of becoming negative are approximately 80 to 90 percent ( this is if viral load becomes undetectable at 4 and 12 weeks).
3. In case you choose interferon and ribavarin , pregnancy should be avoided for 6 months after completion of the treatment as interferon can cause abortions and ribavarin is associaed with teratogenicity.
A six month break should be safe
Hope this helps
Do get back in case you have further queries
Regards
Dr Samir Patil
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Above answer was peer-reviewed by :
Dr. Bhagyalaxmi Nalaparaju
Answered by
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