
What Are The Effects Of Overdose Of Nitrofurantoin?

She should be ok - this isn't a significant overdose.
Detailed Answer:
The usual dose of nitrofurantoin (Macrobid) for a bladder infection (or perhaps it is was prescribed for something else) is 100mg every 12 hours.
Nitrofurantoin can be prescribed up to a total of 400 mg in a day. Your wife will have ingested 300 mg in 24 hours. So while it was more than intended, it isn't in a toxic range.
I am assuming, if she was to take the nitrofurantoin twice a day, that it is a sustained release preparation such as Macrobid. Otherwise nitrofurantoin preparations that are not sustained release are usually prescribed as 50 -100 mg given 4 x /day.
Regardless, she should be fine as she hasn't taken a toxic dose. She should continue to take the medicine as prescribed.
I hope this information gives you some relief!

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