Brief answer...must control your leaking of proteins in urine by lifestyle changes,diet and drugs Detailed answer.... Hello, Thanks for the query. Your protein creatinine ratio is definitely high and indicates that you are passing proteins in your urine which if not checked,can lead to renal failure. You must get 24 hour urine protein estimation done.If the level is between 30-300 mg,then it is microalbuminaria and if greater than 300 mg,then it  is called as macroalbuminaria. Microalbuminaria stage can be reversed by proper medication but if one has macroalbuminaria,then it eventually leads to renal failure,although the progress to stage of renal failure can be delayed. Treatment involves.... Reducing weight. Doing regular exercises Quitting smoking. Controlling your potassium and protein intake. Controlling your diabetes and blood pressure immaculately. Taking ACE inhibitors or ARB's for reduction of blood pressure and taking them even if blood pressure is normal because this helps in slowing the deterioration of kidney functions. Avoiding nephrotoxic drugs  Controlling urinary tract infection promptly ,if any. Please get yourself evaluated properly by consulting a nephrologist and get the proper treatment so as to avoid not only the further damage to your kidneys but also to reverse the damage process. I hope it helps,However you may revert to me for any further query. Best of luck Thanks

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Hello, You are definitely suffering from macroalbuminaria or overt proteinuria. Microalbuminaria is a stage which is potentially reversible but macroalbuminaria is not reversible and generally proceeds to kidney failure in next few years. Treatment at this stage of macroalbuminaria is meant to slow down the progression to the stage of kidney failure. Treatment  involves.... Meticulous control of blood sugar and blood pressure by use of ACE inhibitors and ARB's. Switching to injection insulin from oral antidiabetic drugs. Control of diet and reduction of weight. Reduction of salt intake,potassium intake and protein intake. Quitting smoking. Exercises. Avoiding nephrotoxic drugs  Joint management by a diabetologist and a nephrologist  Once kidney failure takes place,then only treatment option is kidney transplant. Thanks

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