What Are The Side Effects Of Apo-Trazadone,Co-Quetiapine And Alprazolam?

Posted on Fri, 13 Jun 2014

Question: What are the side effects of taking 150 mg of Apo-Trazadone and 100 mg of Co-Quetiapine and 0.5 mg of Alprazolam and 0.5 mg of Alpraz and 15 mg of Apo-Oxazepam?

(with 1-2 glasses of red wine)

Answered by Dr. Shafi Ullah Khan (4 hours later)

Brief Answer:
Side effects mentioned

Detailed Answer:
Thank you for asking!
There are many side effects of these drugs.But we will discuss only those which are reported in more than 10 % of its population.
1) Trazodone has following common side effects.
Blurred vision (11-15%)
Dizziness (20-28%)
Drowsiness (24-40%)
Dry mouth (15-34%)
Fatigue (11-15%)
Headache (16-20%)
Nausea/vomiting (11-15%)

2)Quetiapine has following
Dizziness
Dry mouth
Headache
Somnolence

3)Side effects of alprazolam and alpraz are
Drowsiness (41%)
Depression (10-15%)
Headache (10-15%)
Constipation (10-15%)
Diarrhea (10-15%)
Dry mouth (10-15%)

4)and side effects of oxazepam are
Sedation
Ataxia
Confusion
Memory impairment
Dizziness
Drowsiness
Muscle weakness
Syncope edema
Leukopenia, blood dyscrasias
Decreased libido
Rash
Incontinence
Menstrual irregularities
Jaundice
Blurred vision; diplopia
Plus most of them are anxiolytics and antidepressants and their use together is not allowed as that leads to potentiation of effects by the process of pharmacodynamic synergism and should be avoided.Consult a psychiatrist for the medicines usage and avoid self prescriptions.
I hope it helps.Don't forget to close the discussion please.
Regards
S Khan

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Shafi Ullah Khan (19 hours later)

Thank you Doctor.

The rest (part B)of my question was at the bottom.

What happens if the above are combined and 1-2 glasses of red wine are consumed while taking the above drugs?

If the person claims insomnia, in your professional opinion, the above drugs are definelty not the safe approach, especially with 2 glasses of red wine. It that safe for me to surmise?

Thank you again in advance.

Thank you in advance.

Answered by Dr. Shafi Ullah Khan (35 minutes later)

Brief Answer:
Not advised to be taken together

Detailed Answer:
Thank you for getting back to me!
Please reconsider my last paragraph and see i have addressed it further.I said and i quote " most of them are anxiolytics and antidepressants and their use together is not allowed as that leads to potentiation of effects by the process of pharmacodynamic synergism and should be avoided.Consult a psychiatrist for the medicines usage and avoid self prescriptions ''
Plus red wine itself is a sedative plus it compromises their metabolism and delay them thus further potentiating the issues and no way recommended. Seek a sleep disorder specialist or a psychiatrist and let them take care of your insomnia.Dont self treat that would be lethal.
I hope it clears the mind.Take care and dont forget to close the discussion please.
Regards
S Khan

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar