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What Are The Side Effects Of Prolonged Intake Of Leflunomide?

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Posted on Mon, 27 Jun 2016
Question: i am taking lefno 20 mg and saz 1g bd for moe than five years now last two months i am taking bio injections in addition as per doctor advise. please tell me what is the effect of lefno in long run
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Answered by Dr. Pavan Kumar Gupta (2 hours later)
Brief answer....explained below
Detailed answer....
Hello,
Thanks for the query.
I have read your query and understood your concern.
LEFNO ( LEFLUNOMIDE ) is a diseases modifying anti rheumatic drug and is given for long time.
Short term side effects include nausea vomiting,diarrhoea,rash etc.
Long term side effects include...weightloss,thinning of hair,increase in blood pressure.
Since this drug suppresses your immune system,you become prone to infections like respiratory tract infections,throat infections etc.
Other important side effect includes damage to liver and sometimes may even cause fatal liver failure. That's why one keeps on getting the liver tests done on regular basis to see any damage being caused to liver.
I hope it helps,however you are most welcome to revert to me for any further query.
Best of luck
Thanks
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Pavan Kumar Gupta

General & Family Physician

Practicing since :1978

Answered : 6704 Questions

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What Are The Side Effects Of Prolonged Intake Of Leflunomide?

Brief answer....explained below Detailed answer.... Hello, Thanks for the query. I have read your query and understood your concern. LEFNO ( LEFLUNOMIDE ) is a diseases modifying anti rheumatic drug and is given for long time. Short term side effects include nausea vomiting,diarrhoea,rash etc. Long term side effects include...weightloss,thinning of hair,increase in blood pressure. Since this drug suppresses your immune system,you become prone to infections like respiratory tract infections,throat infections etc. Other important side effect includes damage to liver and sometimes may even cause fatal liver failure. That's why one keeps on getting the liver tests done on regular basis to see any damage being caused to liver. I hope it helps,however you are most welcome to revert to me for any further query. Best of luck Thanks