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What Are The Symptoms Of Hypothyroidism?

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Posted on Mon, 13 Oct 2014
Question: Normal levels of tsh and t4 and low t3. Hypothyroid? I have classic stmptoms of hypothyroid. Thinning eyebrows and hair, tired, muscle pain and dry skin
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Answered by Dr. Muhammed Aslam (1 hour later)
Brief Answer:
TFT not suggestive.

Detailed Answer:
Hi XXXX

Thanks for your query.

The symptoms you mentioned are common in hypothyroidism,but report of your TFT(Thyroid function test) is not suggestive.

In hypothyroidism,the first parameter to be affected is TSH(it becomes high).Then only T3 and T4 become affected.
So changes in levels of T3/T4 in the back ground of a normal TSH level is not supportive of the diagnosis of hypothyroidism.

In such instances,I usually advise my patients to undergo a repeat TFT after about 2 weeks with measurement of Free T3/T4 rather than Total T3/T4.This will give a more clear idea,as total T3/T4 levels are affected by factors like serum protein levels.
You can discuss this with your doctor.

Hope I have answered your query.
Wishing you good health.
Thank you.
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.
Above answer was peer-reviewed by : Dr. Raju A.T
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Answered by
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Dr. Muhammed Aslam

General & Family Physician

Practicing since :2010

Answered : 987 Questions

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What Are The Symptoms Of Hypothyroidism?

Brief Answer: TFT not suggestive. Detailed Answer: Hi XXXX Thanks for your query. The symptoms you mentioned are common in hypothyroidism,but report of your TFT(Thyroid function test) is not suggestive. In hypothyroidism,the first parameter to be affected is TSH(it becomes high).Then only T3 and T4 become affected. So changes in levels of T3/T4 in the back ground of a normal TSH level is not supportive of the diagnosis of hypothyroidism. In such instances,I usually advise my patients to undergo a repeat TFT after about 2 weeks with measurement of Free T3/T4 rather than Total T3/T4.This will give a more clear idea,as total T3/T4 levels are affected by factors like serum protein levels. You can discuss this with your doctor. Hope I have answered your query. Wishing you good health. Thank you.