Question: Hello,
I have had consistently high mpv and high monocyte levels on my blood work. I have systemic lupus and Sjogren's syndrome, but they have been in remission overall. Are these two levels just an indicator or my existing autoimmune diseases? I've been having significant fatigue, headaches, weight gain, hoarseness in voice, LPRD, carpal tunnel syndrome, extremely dry skin, foggy thinking and poor memory. My TSH has been up and down over the past several years with multiple hypothyroidism symptoms...but doctor won't give me medication. I'm 48, and on low dose birth control to possibly treat menopause symptoms with no change of symptoms...no family history of issues in menopause. Two siblings with hypothyroidism and both on medication. Are all of these things pointing more to thyroid issues...and should I get more testing?

I had those Thyroid panel tests done three years ago, and the T3 was low (2.5 pg/mL). The other tests were negative. I do have an appt with endocrinologist on March 18, so I'll push for all of those to be completed again.

I had the CMP (results had MPV & MONOS both high; ABS Lymphs were low, bilirubin low, albumin low, Alpha 1 was high, SED Rate was 16 and has been rising steadily...everything else was normal) and 25 Hydroxy Vit D (result-43.7) done in XXXXXXX of this year at my Rheumatologist appt. I asked her to do the TSH, and that came up as 4.33. She told me to follow up with my PCP. NOTE: My symptoms were at their worst at the time of this January visit.

I did finally get to see my PCP last week (she was out on maternity leave)...she only did the TSH which came up as 2.98, so the T4 wasn't done. She suggested that I was being hyper-vigilant...but I know my body, and something isn't right. I've put my SLE and Sjogren's in remission, and I'm not on ANY medications for them since 2005. I do more diet, exercise, supplements (omegas, multi-vitamin, multi-minerals, vitamin c, vitamin e, glucosamine-chondroitan) meditation, etc.

The reason I'm not on medications for my lupus and sjogren's is BECAUSE I went to XXXXXXX XXXXXXX Center for Integrative Medicine and they made all of the recommendations that have helped put them in remission. My doctor there passed away, and I'm looking for another Integrative Medicine doctor currently.

Thank you for your response! XXXXXXX