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What Causes Anxiety And Panic Attacks While Starting A New Drug?

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Posted on Tue, 1 Sep 2015
Question: Im wondering if having increased anxiety and panic is normal when starting a new med and tirating down from one ? im on day 3 of taking brintellix 5 mg and lowered my dose of pristiq from 100 mg to 50 mg
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Answered by Dr. Shubham Mehta (25 minutes later)
Brief Answer:
yes this can increase anxiety for few days.

Detailed Answer:
Hello
Welcome here.

I understand your concerns.

Starting a new drug and reducing the other, both these factors can increase anxiety and panic initially.

You have started with brintellix. All SSRIs, SNRIs can increase anxiety on drug initiation. Usually, this should settle down in 5-7 days of drug initiation.

Antidepressants, especially SNRIs like effexor and pristiq can cause discontinuation syndrome which mimic the symptoms of anxiety .

A better strategy in my opinion would be to first reach the desired dose of brintellix and then start reducing pristiq.

Kindly discuss this with your doctor.

Hope this helps.

Thanks.
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Above answer was peer-reviewed by : Dr. Neel Kudchadkar
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Answered by
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Dr. Shubham Mehta

Psychiatrist

Practicing since :2008

Answered : 2144 Questions

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What Causes Anxiety And Panic Attacks While Starting A New Drug?

Brief Answer: yes this can increase anxiety for few days. Detailed Answer: Hello Welcome here. I understand your concerns. Starting a new drug and reducing the other, both these factors can increase anxiety and panic initially. You have started with brintellix. All SSRIs, SNRIs can increase anxiety on drug initiation. Usually, this should settle down in 5-7 days of drug initiation. Antidepressants, especially SNRIs like effexor and pristiq can cause discontinuation syndrome which mimic the symptoms of anxiety . A better strategy in my opinion would be to first reach the desired dose of brintellix and then start reducing pristiq. Kindly discuss this with your doctor. Hope this helps. Thanks.