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What Causes Anxiety, Facial Flashes, Cystic Acne, Joint Pain With A Positive AAA Blood Test?

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Posted on Thu, 16 Jan 2014
Question: hello. For the past year i have had a lot of weird symptoms. It all started with facial flushing that started around the same time every night it is also brought on with exercise, heat , anxiety and sex. i am also getting cystic acne on my shoulders and back which started out of no where a couple of years ago and i am still getting them to this day, they are leaving nasty scars and take a long time to heal. I am also getting joint pains in my chest and my left knee. Also noticed increased hair growth on my upper back and chest. lastly i am getting white hair on my head and in my facial hair. I also find myself waking up in the middle of the night 2 or 3 times to use the washroom. So my question is could this be something hormonal in my body creating all these strange symptoms, my doctor cant seem to figure out what is going on. The only thing i have tested postive for is the ANA blood test and have high kidney function.
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Answered by Dr. Shehzad Topiwala (4 hours later)
Brief Answer: Endocrine Detailed Answer: I see the symptoms are varied and unusual. We can rule out a few endocrine conditions by doing the following tests: CBC CMP TSH Free T4 Plasma fractionated metanephrines The above are blood tests. Further, I recommend a 24 hour urine test for 5HIAA. Essentially, we are looking for endocrine problems like thyroid and adrenal. Specifically some of the above tests are meant for rare conditions like Pheochromocytoma and Carcinoid syndrome
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Shehzad Topiwala (31 minutes later)
thanks for your answer, i have done the 5hiaa test and it came back negative i also did a 24 hour urine test for cortisol also negative my thyroid also seems to be ok according to my blood work. Yes my symptoms are unusual, my main concern is the joint pain flushing and the acne on my shoulders which all arrived at the same time. After all the research i have done it keeps coming up with either cushings syndrome or carcinoid. Now i have done a some of the test for them but they came back negative but i also heard that the 24 urine test are not 100% accurate is this correct and are there any other additional test i can take? Thanks again
doctor
Answered by Dr. Shehzad Topiwala (26 minutes later)
Brief Answer: Follow up Detailed Answer: I suggest you do a 24 hour urine test for fractionated catecholamines and metanephrines to evaluate for the possibility of pheochromocytoma. Also add calcitonin to the blood tests. See a dermatologist to assess the skin lesions for the possibility of 'Mastocytosis'
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shehzad Topiwala

Endocrinologist

Practicing since :2001

Answered : 1663 Questions

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What Causes Anxiety, Facial Flashes, Cystic Acne, Joint Pain With A Positive AAA Blood Test?

Brief Answer: Endocrine Detailed Answer: I see the symptoms are varied and unusual. We can rule out a few endocrine conditions by doing the following tests: CBC CMP TSH Free T4 Plasma fractionated metanephrines The above are blood tests. Further, I recommend a 24 hour urine test for 5HIAA. Essentially, we are looking for endocrine problems like thyroid and adrenal. Specifically some of the above tests are meant for rare conditions like Pheochromocytoma and Carcinoid syndrome