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What Causes Diarrhea With Clostridium Difficile Infection Post Dexilant Treatment?

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Posted on Wed, 4 Feb 2015
Question: I have seen bloody diarrhea with C. Diff and post Dexilant treatment,although rare. Have you ever seen these serious reactions? Email XXXXXX
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Answered by Dr. Dr.P.Ratnakar Kini (1 hour later)
Brief Answer:
Dexilant can cause C.diff infection.

Detailed Answer:
Hi,
Thanks for posting your query.
I am Dr.R.K and I am pleased to assist you.

Acid suppressing medications like PPI can cause C.diff infection. Dexilant is a PPI (acid suppressing medication). Normally the acidic environment in the stomach protects against disease causing organism. But when you take acid suppressing medication like dexilant, this acid barrier is lost and it can lead infection of the gut including C.diff. Blood diarrhea is the most severe form of C.diff infection.

So your C.diff infection could be due to dexilant therapy.
You can take metronidazole for relief.

I hope that answers your question.
Let me know if I can assist you further.
Regards,
Dr.R.K.
Note: For further follow up on digestive issues share your reports here and Click here.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr.P.Ratnakar Kini

Gastroenterologist

Practicing since :1994

Answered : 2208 Questions

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What Causes Diarrhea With Clostridium Difficile Infection Post Dexilant Treatment?

Brief Answer: Dexilant can cause C.diff infection. Detailed Answer: Hi, Thanks for posting your query. I am Dr.R.K and I am pleased to assist you. Acid suppressing medications like PPI can cause C.diff infection. Dexilant is a PPI (acid suppressing medication). Normally the acidic environment in the stomach protects against disease causing organism. But when you take acid suppressing medication like dexilant, this acid barrier is lost and it can lead infection of the gut including C.diff. Blood diarrhea is the most severe form of C.diff infection. So your C.diff infection could be due to dexilant therapy. You can take metronidazole for relief. I hope that answers your question. Let me know if I can assist you further. Regards, Dr.R.K.