
What Causes Elevated AST And ALT Levels?

Possible Acute viral hepatitis..
Detailed Answer:
Hello and welcome.
I have read your history carefully.
AST (SGOT) and ALT (SGPT) are reasonably sensitive indicators of liver damage or injury from different typeThe interpretation of elevated AST and ALT results depends upon the entire clinical evaluation of an individuals of diseases or conditions.
All forms of viral and drug induced hepatitis give an elevation of both total and direct bilirubin which clinically presents as jaundice. ALT and AST both are elevated in acute viral hepatitis.
Elevated levels , based on cause can be divided into mild (< 100) , moderate ( 100 to 300) major elevation is greater than 300
the main cause to rule out first , taking into consideration your history is Acute Viral hepatitis.
Other causes may include
Alcoholic or non alcoholic steato hepatitis
Autoimmune hepatitis
Drug induced e.g Paracetamol
Acute on chronic hepatitis i.e flare of chronic hepatitis
I would advise the following initial screening test in my clinic for such rise in LFTs
ultrasound abdomen
Anti HAV igM ,Hbsag n hcvab for hepatitis a , b and c
Autoimmune profile (igm and AMA levels)
Ferritin
Cerruloplasmin
Immunoglobulins
the treatment and further management will depend on the cause of the elevated transaminases
I would advise you to refrain from any drugs that are metabolized in the liver like tylenol or paracetamol for the time being till you consult your doctor.
let me know if you have any query
I will be more than glad to help
thanks

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