Sign-in to Ask A Doctor - 24x7
OR
Sign in with Google
What Causes Elevated MPV Levels?
Question: What does an increasing mpv mean in less tha a year mine has gone up 20 pts. My, platelets are lowering
Brief Answer:
Can be CML. Bone marrow test
Detailed Answer:
Hi
High mean platelet volume (MPV) can be due to chronic myelogenous leukemia (CML) and I would advise you to do a bone marrow test to rule it out.
Bone marrow samples are taken from a bone marrow aspiration and biopsy.
These 2 tests are usually done at the same time. The samples are taken from the back of the pelvic (hip) bone, although in some cases they may be taken from the breastbone (sternum) or other bones.
For a bone marrow aspiration, you lie on a table either on your side or on your belly. After the area is cleaned, the skin over the hip and the surface of the bone is numbed with local anesthetic, which may cause a brief stinging or burning sensation. A thin, hollow needle is then inserted into the bone and a syringe is used to suck out a small amount about 1 teaspoon of liquid bone marrow. Even with the anesthetic, most patients still feel some brief pain when the marrow is removed.
A bone marrow biopsy is usually done just after the aspiration. A small piece of bone and marrow (about 1/16 inch in diameter and 1/2 inch long) is removed with a slightly larger needle that is twisted as it is pushed down into the bone. The biopsy may also cause some brief pain. Once the biopsy is done, pressure will be applied to the site to help prevent bleeding.
These samples are sent to a lab, and they are looked at under a microscope for leukemia cells.
Regards
DR DE
Can be CML. Bone marrow test
Detailed Answer:
Hi
High mean platelet volume (MPV) can be due to chronic myelogenous leukemia (CML) and I would advise you to do a bone marrow test to rule it out.
Bone marrow samples are taken from a bone marrow aspiration and biopsy.
These 2 tests are usually done at the same time. The samples are taken from the back of the pelvic (hip) bone, although in some cases they may be taken from the breastbone (sternum) or other bones.
For a bone marrow aspiration, you lie on a table either on your side or on your belly. After the area is cleaned, the skin over the hip and the surface of the bone is numbed with local anesthetic, which may cause a brief stinging or burning sensation. A thin, hollow needle is then inserted into the bone and a syringe is used to suck out a small amount about 1 teaspoon of liquid bone marrow. Even with the anesthetic, most patients still feel some brief pain when the marrow is removed.
A bone marrow biopsy is usually done just after the aspiration. A small piece of bone and marrow (about 1/16 inch in diameter and 1/2 inch long) is removed with a slightly larger needle that is twisted as it is pushed down into the bone. The biopsy may also cause some brief pain. Once the biopsy is done, pressure will be applied to the site to help prevent bleeding.
These samples are sent to a lab, and they are looked at under a microscope for leukemia cells.
Regards
DR DE
Note: Get a consultation booked to know more about aging related medical issues. Click here.
Above answer was peer-reviewed by :
Dr. Bhagyalaxmi Nalaparaju
Answered by
Get personalised answers from verified doctor in minutes across 80+ specialties
