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What Causes Elevated SGOT And SGPT Levels After Having Saazo?
Question: sir, i m patient of ankylosing spondylitis my treatment undergoing since oct.2013 .i m taking SAAZO 1OOO
per day. moreover my remicade therapy started on 17th may 2014, first dose of 400mg was given on 17th may &second dose of 400mg. was given on 24th XXXXXXX since then my SGOT&SGPT levels are increasing.
27/03/14 ot25 pt36
10/05/14 ot31 pt48
18/06/14 ot51 pt90
22/07/14 ot59 pt97 gradeiii fatty liver 16.3 cm
04/08/14 ot63 pt74
08/08/14 ot93 pt 87
i have stopped taking SAAZO-1000 since one month & now taking UDILIV-300from last 20 days, no other medicine is consumed by me. kindly advice me, what to do
per day. moreover my remicade therapy started on 17th may 2014, first dose of 400mg was given on 17th may &second dose of 400mg. was given on 24th XXXXXXX since then my SGOT&SGPT levels are increasing.
27/03/14 ot25 pt36
10/05/14 ot31 pt48
18/06/14 ot51 pt90
22/07/14 ot59 pt97 gradeiii fatty liver 16.3 cm
04/08/14 ot63 pt74
08/08/14 ot93 pt 87
i have stopped taking SAAZO-1000 since one month & now taking UDILIV-300from last 20 days, no other medicine is consumed by me. kindly advice me, what to do
Brief Answer:
You need not to stopped both saazo and remicade
Detailed Answer:
Hello XXXXXXX
I have read your question and I think you did right by stopping SAAZO . It is a hepatotoxic drug and cause fatty liver. I hope you are not taking Remicade. Because it can also damage liver.
Now for next 3 months avoid any hepatotoxic medication like Methotexate . Also do not take pain killers like tramadol which get metabolise mainly in liver.
I would also request you to avoid fatty diet.
Your hepatic enzymes are not very high and your liver damage is still reversible. Everything will be normal in some time. There is liver medicine LIV 52 which you can take after discussing with your doctor.
Once your liver is normal you can start low doses SAAZO. Do not take both SAAZO and Remicade. As both have additive side effect on liver.
I hope these measures will be useful for you. Let me know if there is any followup question.
Thanks.
You need not to stopped both saazo and remicade
Detailed Answer:
Hello XXXXXXX
I have read your question and I think you did right by stopping SAAZO . It is a hepatotoxic drug and cause fatty liver. I hope you are not taking Remicade. Because it can also damage liver.
Now for next 3 months avoid any hepatotoxic medication like Methotexate . Also do not take pain killers like tramadol which get metabolise mainly in liver.
I would also request you to avoid fatty diet.
Your hepatic enzymes are not very high and your liver damage is still reversible. Everything will be normal in some time. There is liver medicine LIV 52 which you can take after discussing with your doctor.
Once your liver is normal you can start low doses SAAZO. Do not take both SAAZO and Remicade. As both have additive side effect on liver.
I hope these measures will be useful for you. Let me know if there is any followup question.
Thanks.
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Above answer was peer-reviewed by :
Dr. Bhagyalaxmi Nalaparaju
Answered by
Dr. Dr. Naveen Kumar Sharma
Orthopaedic Surgeon, Joint Replacement
Practicing since :2002
Answered : 4486 Questions
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