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What Causes Fatigue, Depression And Anxiety While On Methimazole?
Question: My wife has Graves Disease(hyperthyroid) that went undiagnosed & untreated for 4 to 5 years. She has been taking methimazole for several months. Her TSI is 144, T4 0.9, TSH 3.47 from her latest lab test. She still has lots of fatigue, itchy skin(scratching causing blisters and bleeding), depression, anxiety, poor memory and concentration, and now a low resting pulse rate(54). She sees her endocrinologist next week. We have read that some people with similar cases have adrenal problems, should we ask her endocrinologist about that? Also what are the effects of long term untreated graves disease? We can't find any studies that address this.
Brief Answer:
Grave's disease
Detailed Answer:
Good day,
Noted your concern. Grave's disease is an autoimmune disease and many other auto immune diseases can be associated with Grave's disease. Adrenal disorders, especially addison's disease is often associated. It causes low cortisol hormone, fatugue and tiredness. Vitamin B12 deficiency ( pernicious anemia) is another important association. You should discuss with your endocrinoloist about these issues.
They are correctable.
Long term untreated Grave's disease can cause weakneing of heart, irregular heart beats ( atrial fibrillation), weak bones ( osteoporosis) etc.
regards
Binu
Grave's disease
Detailed Answer:
Good day,
Noted your concern. Grave's disease is an autoimmune disease and many other auto immune diseases can be associated with Grave's disease. Adrenal disorders, especially addison's disease is often associated. It causes low cortisol hormone, fatugue and tiredness. Vitamin B12 deficiency ( pernicious anemia) is another important association. You should discuss with your endocrinoloist about these issues.
They are correctable.
Long term untreated Grave's disease can cause weakneing of heart, irregular heart beats ( atrial fibrillation), weak bones ( osteoporosis) etc.
regards
Binu
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Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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