Brief Answer:
Hi I would recommend the following.

Detailed Answer:
Dear sir,

polycythemia vera is an acquired condition and hemochromatosis is an inherited condition and sometimes can be confused.
can you please send me your bood and bone marrow report as well aa jak2stat mutation study.

i hope this helps.
let me know if you have any other concern sir.
sincerely,
Dr Parth Desai

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Brief Answer:
Hi I would recommend the following.

Detailed Answer:
Dear Mam,

Thank you for your reply and the reports. After reviewing them, I think that the diagnosis of Polycythemia vera needs to be relooked at and reviewed if possible. Your hemoglobin is 17 which is what is called as erythrocytosis and is seen in Polycythemia Vera but apart from Polycythemia Vera there are many other causes of erythrocytosis due to secondary conditions like abnormal hemoglobins, smoking, heart or lung problems etc. It can be seen but it is actually very rare to see high iron stores (ferritin) in Polycythemia Vera. For accurate diagnosis of Polycythemia vera a bone marrow biopsy, JAK2STAT mutation study and Serum Erythropoeitin levels are very essential.

Occurence of 2 diseases at the same time is always a possibility but we rule that in only after the more commoner event i.e a common disease is first ruled out.

So all in all my recommendation is to Consult your hematologist and ask him about the JAK2STAT molecular testing, Bone marrow biopsy and Serum erythropoeitin levels check up to confirm the diagnosis of Polycythemia and then go on from there. As far as Iron overload is considered it can be addressed after this and may require further work up for ruling out conditions that cause hemochromatosis and iron chelation therapy/phlebotomy according to organ involvement and ferritin levels/bone marrow iron storage measurement.

I hope this helps mam.
Let me know if you have any other concern mam.

Sincerely,

Dr Parth Desai

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