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What Causes High Liver Enzymes?

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Posted on Wed, 10 Sep 2014
Question: I was told by my dr my liver enzymes are high. could this be from the meds I take zolft and tramadol
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Answered by Dr. Bhagyalaxmi Nalaparaju (1 hour later)
Brief Answer:
Zoloft can increase liver enzymes.

Detailed Answer:
Hello.

Zoloft (Sertraline) is selective serotonin reuptake inhibitor(SSRI) and it can increase liver enzymes mostly serum aminotransferase. But most individuals have asymptomatic aminotransferase rise. You can discuss about this doctor and he/she may reduce the dosage of medication or switch over to other ssri medication.

Tramadol in heavy doses can cause mild elevation of liver enzymes without causing any clinical symptoms. Over doses can cause liver injury.

Hope I have answered your query.
If you have any queries I will be happy to help you.
Thank you.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Bhagyalaxmi Nalaparaju

General & Family Physician

Practicing since :2007

Answered : 492 Questions

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What Causes High Liver Enzymes?

Brief Answer: Zoloft can increase liver enzymes. Detailed Answer: Hello. Zoloft (Sertraline) is selective serotonin reuptake inhibitor(SSRI) and it can increase liver enzymes mostly serum aminotransferase. But most individuals have asymptomatic aminotransferase rise. You can discuss about this doctor and he/she may reduce the dosage of medication or switch over to other ssri medication. Tramadol in heavy doses can cause mild elevation of liver enzymes without causing any clinical symptoms. Over doses can cause liver injury. Hope I have answered your query. If you have any queries I will be happy to help you. Thank you.