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What Causes Itching Of Legs And Buttocks At Night?

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Posted on Fri, 16 Jan 2015
Question: What causes itching that begins each night at around 8:00 for about one hour usually is in both legs sometimes travel to arms and buttock.
doctor
Answered by Dr. Praveen (1 hour later)
Brief Answer:
Could you please share some more information?

Detailed Answer:
Hi dear.Thanks for your query.

Itching is one of the side effects of Contrave.

I would like to know some more information-
Since how long do you have itching?
Is the area red?Can you see tiny bumps in the affected area?Swelling?
Do you have fever?
Do you have any history of allergy?known food allergy?known drug allergy?
Do you suspect mosquitoes when you go to sleep?One species(Aedes mosquito bites on legs).
Could you upload the snaps of the affected areas so that they can be examined?

Await your reply soon.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Praveen (9 hours later)
I looked up contraindications for Contrave. I am taking a low dose beta blocker for got to mention. approximately 12 hours after the morning dosing I notice the itching. I also experienced heart palpitations last night and headache probably due to spike in blood pressure. I never have these symptoms. Since contrave is a opiate why would the symptoms appear so many hours after taking the morning dose which is always around 8:00 am. The other symptoms of itching and heart palpatations start almost 12 hours later exactly. I think I am going to stop taking. can't stand the headached that has started at nighttime.

One good side effect the entire muscle pain I havre had for years is no long er present. Like a fibromyalgia type of pain. Is this due to the wellbutrin component of the med. I notice the x was pulled by the fda after some clinical trials. is it back on the market?

itching did not have a rash last night. looks like diaper rash when present. then goes away when itching stops. no fever. but headaches started last two days probably due to a spike in BP/ only when itching started around 12 hours after one time dosing at 8 in the morning. starts exactly 12 hours after initial and only dose for the day. i am dairy intolerant. no known rx allergy. no mosquitoas in house.
area no red and no fever
doctor
Answered by Dr. Praveen (2 hours later)
Brief Answer:
Contrave can cause high BP and heart rate

Detailed Answer:
Hi dear.Thanks for sharing the information.

Contrave contains Naltrexone/Bupropion.Buprion is a component of Wellbutrin.

Cotrave can cause itching and headache as side effects(these are to relative contraindications in individuals with these symptoms).These side effects need not have any relation to time to their onset(can appear any time).

Contrave is approved by FDA especially for weight management for adults with high BMI with hypertension(or diabetes or high cholesterol).This is the recent approval as on September 10 2014.Though this approval is based on the recent trial data, FDA has insisted the requirement of postmarketting surveillance reports of Contrave to evaluate the cardiac safety(since patients with heart disease were excluded from these clinical trial).

I hope your blood pressure(BP) is well controlled.Since Contrave can cause high blood pressure(contraindicated especially in individuals with uncontrolled BP) and increased heart rate I were to regularly monitor BP and heart rate especially when if your BP is high and it is present before starting the therapy.This is very vital to decide whether the drug should be continued.

Yes, the good side effect which you have made a mention is because of its opioid analgesic activity(Natrexone) which relieves your pain.

Hope I have answered your query.
Note: Hope the answers resolves your concerns, however for further guidance of skin related queries consult our Dermatologist.Click here to book a consultation

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Praveen

General & Family Physician

Practicing since :2008

Answered : 1055 Questions

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What Causes Itching Of Legs And Buttocks At Night?

Brief Answer: Could you please share some more information? Detailed Answer: Hi dear.Thanks for your query. Itching is one of the side effects of Contrave. I would like to know some more information- Since how long do you have itching? Is the area red?Can you see tiny bumps in the affected area?Swelling? Do you have fever? Do you have any history of allergy?known food allergy?known drug allergy? Do you suspect mosquitoes when you go to sleep?One species(Aedes mosquito bites on legs). Could you upload the snaps of the affected areas so that they can be examined? Await your reply soon.