Brief Answer: You have several symptoms of Depression. Detailed Answer: Hello, Thanks for your query. I appreciate your efforts for medical consultation in so much distress. Important aspects of your query are: • 30 year old female • Duration of problem. • Complaints of: lack of energy, disliking self, change in personality, sadness all time, feeling of emptiness, lack of appetite, lack of interest in job and poor sleep. From the description it appear that you have depression. Lack of energy, disliking self, change in personality, sadness all time, feeling of emptiness, lack of appetite, lack of interest in job and poor sleep: all are symptoms of Depression. Other symptoms of Depression which may or may not be present in your case: anxiety, restlessness, mild irritability, excessive worry regarding own health, muscle spasm, heaviness in body, headache, palpitation and dry mouth. Depression occurs due to neurotransmitters imbalance in brain most commonly involving serotonin neurotransmitter. You need treatment with psychiatrist to treat your depression. It is not clear if you received any treatment in past, but believe me people life changes after treatment. There is need for treatment, if symptoms cause significant personal distress or affect personal/professional life like in your case. Both drug and non drug treatment like cognitive behaviour therapy (form of psychotherapy) are used for treatment. Choice of treatment depends on severity of symptoms, personal preference and availability of treatment. In drug treatment two types of medicine used. For immediate relief of distress benzodiazepines group of medicines are used and for long term relief most commonly SSRI (selective serotonin reuptake inhibitors) are used. SSRI takes around 3-4 weeks to show its effect. Non drug treatment like cognitive behaviour therapy (form of psychotherapy) also takes weeks to show its effect. Apart from above advice following simple measures will help you: -Daily morning walk -Follow structured daily routine. Fix sleep and wake up time. -Do not use excessive caffeine (tea, coffee and cold drink) -Stop substance use like alcohol (If present in your case) -Breathing exercise, yoga and meditation (which you can learn from some nearby expert) So, take first step towards treatment and meet nearby psychiatrist for help. I believe you will be well soon. I hope this information has been both informative and helpful for you. In case of any doubt, I will be available for follow ups. Wish you good health. Regards,

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