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What Causes Low Body Temperature In A Person With JAK2 Mutation And Diabetes?

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Posted on Mon, 21 Dec 2015
Question: I have quite the list of chronic long term health issues, many of them wrapped around a diagnosed jak 2 mutation and the blood clotting issues that come with such a thing. and diabetes. the latest was last weeks mild stroke. I am an avid fan of healthy eating and following the advice and med instructions of the six specialists I see regularly and just had a phlebotomy three weeks ago. another noticeable thing is an abnormally low body temperature (apx 94.9 to 96.7 during times of activity such as house cleaning) and during activity can become quckly short of breath, and extremely heavy episodes of sweating and am now at an appx time limit of less then ten minutes of ability of staying active without rest. it used to be 8 to 16 hours when I was actively employed. so the questions: Is there anything abnormal in this range of body temperature with appx 97.4 as normal non active range. Is there any illnesses that are a cause of this as the center symptom? Can this range of body temperature cause any health issues especially blood clotting issues or cause any sort of issues with the flow of blood in the body? is it anything abnormal to have that low of body temperatures not involving cold weather or exposure to situations which cause body to be exposed to cold? How low is considered too low when it does not involve exposure to low temperatures or any sort of exposure to outside conditions or temperatures?
doctor
Answered by Dr. Hardik Sanghvi (13 hours later)
Brief Answer:
You have low body temperature and you need to search the cause.

Detailed Answer:
Hi, dear
I have gone through your question. I can understand your concern.
Your body temperature ranges from 94.9 to 96.7 at time of activities.

Normal temperature is 97.7 to 99.5 degree ferenhit.

Our body process and all activities in body are at optimal level with this temperature. Anything below or above this temperature affect the function of all systems.

Your temperature is low without exposure to cold so that is definitely abnormality. You need to search the cause and take treatment.

There are many causes of low body temperature. Hypothyroidism and aderenal abnormality are the most common cause. Diabetes, renal and kidney disease, sepsis, low progesterone all can leads to low body temperature.

You need to search the cause.


Of course low body temperature leads the fluid more vicious and its difficult to push the fluid and leads to thicker blood and clotting issues.

You also have chronic myeloproliferative disease confirmed by jak 2 mutation.

Chronic myeloproliferative disease like polycythemia vera and essential thrombocythemia itself increase the thickness of blood due to overproduction of rbcs and platelets and leads to clotting abnormality.


Your mild stroke may be due to chronic myeloproliferative disease along with low body temperature.
Because both increase the tendency of blood clotting.

You should take low dose aspirin to prevent thrombosis.

Drugs like hydroxyurea can be used. You need through investigation to search the cause of low body temperature.

Consult your doctor and plan accordingly.
Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic. Wish you a very good health.


phlebotomy is the treatment of choice for polycythemia vera.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Hardik Sanghvi (3 days later)
with this information of low body temperature, knowing I already take aspirin and Plavix daily as well as nadoral for esophageal vericies and glipizide and lantus for diabetes, and phlebotomies every three months for jak 2 mutation with an intolerance of hydroxyuria from past experience, would there be any advantages in what could be medical treatments to come from investigation and discoveries of any abnormal causes of low body temperature that is not already been put into play or would it seem only waste of time and money overkill to check into other possibilities?
doctor
Answered by Dr. Hardik Sanghvi (3 hours later)
Brief Answer:
No you need to go for through investigation.

Detailed Answer:
Hi, dear
I have gone through your question. I can understand your concern. You are taking aspirin, plavix, anti diabetic drugs and regular phlebotomy. However you should go for through investigation to search exact cause. Then you should take treatment accordingly. It will definitely help to specialize the treatment. Like hypothermia due to thyroid or aderenal cause need special treatment. So search for the cause and take treatment accordingly.
Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic. Wish you a very good health.
Above answer was peer-reviewed by : Dr. Sonia Raina
doctor
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Follow up: Dr. Hardik Sanghvi (2 hours later)
what sort of specialist would I want to see for such an investigation
doctor
Answered by Dr. Hardik Sanghvi (1 hour later)
Brief Answer:
You should consult haematologist.

Detailed Answer:
Hi, dear
I have gone through your question. I can understand your concern.
You should consult haematologist to search the cause. Then you should take treatment according to diagnosis.
Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic. Wish you a very good health.
Above answer was peer-reviewed by : Dr. Sonia Raina
doctor
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Follow up: Dr. Hardik Sanghvi (4 hours later)
thank you for you prompt and thorough responses in these questions. i already see a hematologist for the jak 2 mutation, and recieve phlebotomies every 3 months and i must say, that all by itself, for being such a simple thing has made all the difference in the world until recently when the sudden occurance of the stroke came into my life. it was quite a shock since i eat correctly, take meds religiously and just plain didnt expect it. the problem i have ran across is the reluctance/refusal of this doc to do further testing.. he seems satisfied with the little info he already kinows, which was provided by other places and the few times i have approached him about testing for other things, his response was that he was a doctor who provides treatments and not testing.. Is there a difference in this type lf specifics in specialists that not only i need a hematologis but one who specializes in testing for stuff... this has confused me quite a bit with all 5 specialist i have, that doesnt seem to make sense to me. it seems like it would need to be known the "why" to effectivelly treat any illness....
doctor
Answered by Dr. Hardik Sanghvi (15 hours later)
Brief Answer:
You should go for testing in laboratory by pathologist.

Detailed Answer:
Hi, dear
I have gone through your question. I can understand your concern.
You took medicine regularly and you ate correctly but your stroke is due to myeloproliferative disease with high clotting tendency.


You need through investigation to search exact type of myeloproliferative disease and exact cause of hypothermia which we discussed earlier.

Regarding testing your haematologist will prescribe all these testing and these are to be done by pathologist in laboratory.

You should go for through investigation andtatake treatment accordingly.

Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic. Wish you a very good health.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Hardik Sanghvi (2 days later)
thank you for your answers. it has helped me to understand some of the more confusing stuff a great deal. I appreciate your assistance and the availability given through this website. sincerely.....
doctor
Answered by Dr. Hardik Sanghvi (5 hours later)
Brief Answer:
You are most welcome.

Detailed Answer:
You are most welcome.
Thanks for using health care magic.
Wish you a very good health.
If you don't have any further questions then please close the discussion and rate the answer.
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Hardik Sanghvi (27 hours later)
one more please. what is the typical causes of low lymphocyte/high neutrophil combo in lab results, if hiv has already showed as negative..
doctor
Answered by Dr. Hardik Sanghvi (4 hours later)
Brief Answer:
Infection can leads to low lymphocytes and high neutrophil.

Detailed Answer:
Hi, dear
I have gone through your question. I can understand your concern.
Almost all bacterial infection can leads to low lymphocytes and high neutrophil count. Hiv positive or negative doesn't matter.
If you have any infection then you should take antibiotics treatment accordingly.
Hope I have answered your question, if you have doubt then I will be happy to answer.
Thanks for using health care magic. Wish you a very good health.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Hardik Sanghvi (3 hours later)
what is the reasons doctor's are refusing to prescribe antibiotics these days
/
doctor
Answered by Dr. Hardik Sanghvi (52 minutes later)
Brief Answer:
To avoid unnecessary treatment.

Detailed Answer:
Hi, dear
I have gone through your question. I can understand your concern.
May be you don't need antibiotics. So doctor's are refusing to avoid unnecessary antibiotics. Moreover it leads to resistance development. So better to avoid unnecessary antibiotics. If you feel that you have infection then you can go for CRP test.

If CRP is positive then you need antibiotics.


Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic. Wish you a very good health.
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Hardik Sanghvi

Hematologist

Practicing since :2008

Answered : 7043 Questions

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What Causes Low Body Temperature In A Person With JAK2 Mutation And Diabetes?

Brief Answer: You have low body temperature and you need to search the cause. Detailed Answer: Hi, dear I have gone through your question. I can understand your concern. Your body temperature ranges from 94.9 to 96.7 at time of activities. Normal temperature is 97.7 to 99.5 degree ferenhit. Our body process and all activities in body are at optimal level with this temperature. Anything below or above this temperature affect the function of all systems. Your temperature is low without exposure to cold so that is definitely abnormality. You need to search the cause and take treatment. There are many causes of low body temperature. Hypothyroidism and aderenal abnormality are the most common cause. Diabetes, renal and kidney disease, sepsis, low progesterone all can leads to low body temperature. You need to search the cause. Of course low body temperature leads the fluid more vicious and its difficult to push the fluid and leads to thicker blood and clotting issues. You also have chronic myeloproliferative disease confirmed by jak 2 mutation. Chronic myeloproliferative disease like polycythemia vera and essential thrombocythemia itself increase the thickness of blood due to overproduction of rbcs and platelets and leads to clotting abnormality. Your mild stroke may be due to chronic myeloproliferative disease along with low body temperature. Because both increase the tendency of blood clotting. You should take low dose aspirin to prevent thrombosis. Drugs like hydroxyurea can be used. You need through investigation to search the cause of low body temperature. Consult your doctor and plan accordingly. Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic. Wish you a very good health. phlebotomy is the treatment of choice for polycythemia vera.