
What Causes Missed Abortion With Normal Reports?

Question: Hi,
Background :
"As per Ultrasound (TVS) my wife is having a pregnancy of 4 weeks and 5 days and we gone through the test of HCG twice within 48 hours and its showing 2608 and after 48 hours its showing 2777 and PROGESTERONE, SERUM is 4.4. so the next suspect is whether baby is on tube but we did the ultrasound and as per report its normal.
Apart from this doctor suggested every alternative Sustan 200 (injunction) and Sustan 400 mg put in XXXXXXX (twice in a day)
This question is continuation of next last question about Pregnancy. Well today (05th September ) we went for Ultrasound and doctor reports said that "Single pulseless embryo 03mm in CRL : 6+0, Concl : Missed Abortion."
My wife went through DNC on 8th September and samples has been given to lab for kerotyping. As you recommended for kerotyping which will give us a root cause for abortion.
Today we received the report of kerotyping and looks like the reports are normal. . Please have a look and advise
Report :
CYTOGENETIC PROFILE:
1. AUTOSOMES: 44
2. SEX CHROMOSES : 2
3. TOTAL CHROMOSES NUMBER : 46
4. TRANSLOCATION: Nil
5. INVERSION : Nil
6. DELETION : Nil
COMMENTS: The fetus had a normal cytogenetic profile with no chromosomal detected.
Please advise.
Background :
"As per Ultrasound (TVS) my wife is having a pregnancy of 4 weeks and 5 days and we gone through the test of HCG twice within 48 hours and its showing 2608 and after 48 hours its showing 2777 and PROGESTERONE, SERUM is 4.4. so the next suspect is whether baby is on tube but we did the ultrasound and as per report its normal.
Apart from this doctor suggested every alternative Sustan 200 (injunction) and Sustan 400 mg put in XXXXXXX (twice in a day)
This question is continuation of next last question about Pregnancy. Well today (05th September ) we went for Ultrasound and doctor reports said that "Single pulseless embryo 03mm in CRL : 6+0, Concl : Missed Abortion."
My wife went through DNC on 8th September and samples has been given to lab for kerotyping. As you recommended for kerotyping which will give us a root cause for abortion.
Today we received the report of kerotyping and looks like the reports are normal. . Please have a look and advise
Report :
CYTOGENETIC PROFILE:
1. AUTOSOMES: 44
2. SEX CHROMOSES : 2
3. TOTAL CHROMOSES NUMBER : 46
4. TRANSLOCATION: Nil
5. INVERSION : Nil
6. DELETION : Nil
COMMENTS: The fetus had a normal cytogenetic profile with no chromosomal detected.
Please advise.
Brief Answer:
Yes the report is normal.
Detailed Answer:
Dear XXXXXX,
Yes the karyotype is NORMAL.
So now the cause is most probably idiopathic, i.e. spontaneous abortion without any cause.
There are also other causes too like Infection for which a CBC and TORCH & APLA test is done.
You can get these done in any good lab.
But let me inform you that there is a possibility that these tests might ALSO come normal.
But if it comes positive then we know what to do next before you start trying for next pregnancy.
Regards,
Dr. Som MD
XXXXXXX
Yes the report is normal.
Detailed Answer:
Dear XXXXXX,
Yes the karyotype is NORMAL.
So now the cause is most probably idiopathic, i.e. spontaneous abortion without any cause.
There are also other causes too like Infection for which a CBC and TORCH & APLA test is done.
You can get these done in any good lab.
But let me inform you that there is a possibility that these tests might ALSO come normal.
But if it comes positive then we know what to do next before you start trying for next pregnancy.
Regards,
Dr. Som MD
XXXXXXX
Above answer was peer-reviewed by :
Dr. Ashwin Bhandari

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