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What Causes Severe Headache After Having Cortisone Shot?

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Posted on Fri, 7 Aug 2015
Question: I had a cortisone shot in my knee yesterday and last night I got this unrelenting HA. I took AllegraD, and Alevex2, and Tylenol 1000mg this am with without any relief. Coukd this be the result of the cortisone shot?
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Answered by Dr. Het Ram Bishnoi (8 hours later)
Brief Answer:
Cortisone Injection and HEADACHE

Detailed Answer:
Hello XXXXX
You got cortisone shot and after few hours developed headache ( unbearable).
Question "Could this be the result of the cortisone shot"?
Yes, sometimes cortisone shot raises intracranial pressure and produces headache .
In your case headache may be due to cortisone shot .
But this is short lasting and you will get relief within a short period .
Cortisone readily enter the brain and can influence mood, sleep patterns and EEG activities ( this may be the reason of headache , due to this possibility you didn't got complete relief with medicines).
So wait sometime and you will get relief.
Good luck.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by : Dr. Raju A.T
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Answered by
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Dr. Het Ram Bishnoi

General & Family Physician

Practicing since :1978

Answered : 6271 Questions

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What Causes Severe Headache After Having Cortisone Shot?

Brief Answer: Cortisone Injection and HEADACHE Detailed Answer: Hello XXXXX You got cortisone shot and after few hours developed headache ( unbearable). Question "Could this be the result of the cortisone shot"? Yes, sometimes cortisone shot raises intracranial pressure and produces headache . In your case headache may be due to cortisone shot . But this is short lasting and you will get relief within a short period . Cortisone readily enter the brain and can influence mood, sleep patterns and EEG activities ( this may be the reason of headache , due to this possibility you didn't got complete relief with medicines). So wait sometime and you will get relief. Good luck.