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What Causes Sudden Loss Of Stamina And Abnormal Red Blood Cells?

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Posted on Mon, 27 Oct 2014
Question: my husband is a high energy person, especially for his age. recently he has been experiencing lack of stamina and energy as well as looking pale. his blood work shows "abnormal red blood cells" and a bone marrow test has been ordered. My husband did not ask any questions and the doctor did not volunteer any possible causes for this condition. I am concerned and would like to know what are some of the potential causes of this condition.

doctor
Answered by Dr. Jyothi B L (54 minutes later)
Brief Answer:
Possible myelodysplasia

Detailed Answer:
Hi,
Thanks for asking
I am Dr Jyothi BL and will be answering your query.

Looking at the query, my opinion is as follows:

1. Looks possible myelodysplastic syndrome, like blast cells, leukoerythroblastic blood picture, etc.
2. However, megaloblastic anemia or poikilocytosis in severe iron deficiency anemia cannot also be ruled out.
3. Please attach reports, based on which I will try to help you further

Hope it helps.

Any further queries, happy to help again.

Dr. Jyothi BL

Above answer was peer-reviewed by : Dr. Ashwin Bhandari
doctor
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Follow up: Dr. Jyothi B L (10 hours later)
Thank you for your response. After further discussion with my husband this morning, I learned the following; His primary care physician referred him to a specialist because of low platelets. The specialist read a new blood analysis and told my husband that the platelet count was normal at that time but that another anomaly was discovered. The doctor said that normal red blood cells are round. However, in my husband's case, they have uneven edges and are not round, thus the request for the bone marrow test. In this situation does your diagnosis remain the same?
Thanks again.
doctor
Answered by Dr. Jyothi B L (11 hours later)
Brief Answer:
Bone marrow lesion. require reports.

Detailed Answer:
Hi,
Thanks for asking again.

Looking at the new details, uneven edges are commonly seen in enzyme deficiencies or renal disorders. However, at this age, its uncommon and this appears to be not. None of the above, require, bone marrow biopsy for confirmation.

Until a bone marrow test report is available, I would still think of a possibility of myelodysplasia as abnormal Rbc can also be seen in this condition. If more reports are available, and if you can attach it, I can be more accurate.
Other causes, that require a bone marrow, without a marrow occupying lesion is rare at this age.

Hope it helps. Any further queries, happy to help again.

Dr. Jyothi BL
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Shanthi.E
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Answered by
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Dr. Jyothi B L

Pathologist and Microbiologist

Practicing since :2003

Answered : 849 Questions

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What Causes Sudden Loss Of Stamina And Abnormal Red Blood Cells?

Brief Answer: Possible myelodysplasia Detailed Answer: Hi, Thanks for asking I am Dr Jyothi BL and will be answering your query. Looking at the query, my opinion is as follows: 1. Looks possible myelodysplastic syndrome, like blast cells, leukoerythroblastic blood picture, etc. 2. However, megaloblastic anemia or poikilocytosis in severe iron deficiency anemia cannot also be ruled out. 3. Please attach reports, based on which I will try to help you further Hope it helps. Any further queries, happy to help again. Dr. Jyothi BL