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What Causes Sudden Rise Of Serum PSA?

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Posted on Thu, 24 Jul 2014
Question: Good afternoon,
Age 60; PSA of 1.6 from 05/2013; PSA 12.3 from 06/30/2014; have standing Dx of BPH;
Can this sudden jump be due to BPH? PSA was stable in years prior with values of 1.4,; 1.6
doctor
Answered by Dr. Dr. P. T. Patil (2 hours later)
Brief Answer:
Needs to rule out Cancer of Prostate.

Detailed Answer:
Hello
Thanks for your query,based on the facts that you have posted it appears that you have
sudden rise of your Serum PSA from 1.6 to 12.3 over a period of 6 weeks which otherwis was stable over last few years.

Serum PSA is a basic tool in screening for cancer of the prostate .It may get raised in acute infection of prostate and BPH.However one has to rule out cancer of prostate by doing ultrasound guided multi-core biopsy of prostate .

Please consult qualified Urologist for clinical and digital rectal examination and Biopsy of the prostate to be rest assured about presence cancer of Prostate.

Hope I have answered your query ,please feel free to ask if you have more questions ,
I shall be happy to help you
Thanks and Regards.
Dr.Patil.


Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. P. T. Patil (13 hours later)
The rise from 1.6 to 12.3 took place over one year, not six weeks.
I have an appointment scheduled with the Urologist for DRE and know he will want to do biopsy to rule out Cancer of Prostate.

The question is the following; In your experience have you seen a rise of 1.6 to 12.3 over one year due to BPH?
doctor
Answered by Dr. Dr. P. T. Patil (9 hours later)
Brief Answer:
Yes it does bets increased.

Detailed Answer:
Hello
Thanks for follow up.
Serum PSA do increases in BPH however it is normal routine protocol to rule out cancer of prostate by doing Prostate biopsy.

Other option which I normally follow is to prescribe antibiotics and alpha adrenargic receptor blockers like Tomsulosin and Dutasteride for 3 weeks and repeat serum PSA after three weeks. You may want to discuss about this option when you visit the doctor.

Thanks and Regards.
Dr.Patil.
Note: Consult a Urologist online for consultation about prostate and bladder problems, sexual dysfunction, kidney stones, prostate enlargement, urinary incontinence, impotence and erectile dysfunction - Click here.

Above answer was peer-reviewed by : Dr. Prasad
doctor
Answered by
Dr.
Dr. Dr. P. T. Patil

Urologist

Practicing since :1971

Answered : 10589 Questions

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What Causes Sudden Rise Of Serum PSA?

Brief Answer: Needs to rule out Cancer of Prostate. Detailed Answer: Hello Thanks for your query,based on the facts that you have posted it appears that you have sudden rise of your Serum PSA from 1.6 to 12.3 over a period of 6 weeks which otherwis was stable over last few years. Serum PSA is a basic tool in screening for cancer of the prostate .It may get raised in acute infection of prostate and BPH.However one has to rule out cancer of prostate by doing ultrasound guided multi-core biopsy of prostate . Please consult qualified Urologist for clinical and digital rectal examination and Biopsy of the prostate to be rest assured about presence cancer of Prostate. Hope I have answered your query ,please feel free to ask if you have more questions , I shall be happy to help you Thanks and Regards. Dr.Patil.