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What Causes Swelling In The Legs While On Trandate?

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Posted on Thu, 27 Oct 2016
Question: Hi ....my sister has high bloodpressure and her dr prescripted trandate , hydralazine and lasix but after she takes them her legs feel weak and tired and swollen. Will those do that?
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Answered by Dr. Ilir Sharka (59 minutes later)
Brief Answer:
I would recommend as follows:

Detailed Answer:
Hello!

Thank you for asking on HCM!

I carefully passed through your question and would explain that her symptoms could be related to hydralazine adverse effects.

From the other hand trandate as a betablocker can cause a low hear rate and a low physical performance.

I recommend discussing with her attending physician on the possibility of stopping hydralazine and switch to another antihypertensive drug like an ACE inhibitor (lisinopril, ramipril) or an ARB (valsartan, telmisartan).

I would also advise you to closely monitor her heart rate. Trandate dose may need to be reduced based on her heart rate, if she is having a low heart rate (bradycardia could cause fatigue and weakness).

You should discuss with her attending physician on the above issues.

Hope to have been helpful!

Kind regards,

Dr. Iliri

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ilir Sharka

Cardiologist

Practicing since :2001

Answered : 9533 Questions

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What Causes Swelling In The Legs While On Trandate?

Brief Answer: I would recommend as follows: Detailed Answer: Hello! Thank you for asking on HCM! I carefully passed through your question and would explain that her symptoms could be related to hydralazine adverse effects. From the other hand trandate as a betablocker can cause a low hear rate and a low physical performance. I recommend discussing with her attending physician on the possibility of stopping hydralazine and switch to another antihypertensive drug like an ACE inhibitor (lisinopril, ramipril) or an ARB (valsartan, telmisartan). I would also advise you to closely monitor her heart rate. Trandate dose may need to be reduced based on her heart rate, if she is having a low heart rate (bradycardia could cause fatigue and weakness). You should discuss with her attending physician on the above issues. Hope to have been helpful! Kind regards, Dr. Iliri