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What Causes Weight Gain And Swollen Face While On Wysolone?

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Posted on Thu, 12 Nov 2015
Question: My father is taking wysolone 7.5 mg for 2 years now after his surgery of pituitary adenoma. He is also Diabitic and takes insulin. However, he has gain weight and having moon face as well as swelling in his leg perhaps side effect of wysolone. Now, neurosurgeon has confirmed that he has fully recovered from the surgery. Shall he stop wysolone ? If yes how slowly?
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Answered by Dr. Shehzad Topiwala (2 hours later)
Brief Answer:
Yes

Detailed Answer:
Your father needs to be see in-person by an endocrinologist. This is because management of a person who has had pituitary surgery and is on steroids plus others hormones such as euthyrox and insulin, requires specialised care.

Endocrinologists have advanced training in these matters. They are complex to deal with and hence expert care is necessary.

For example, it appears prudent to withdraw wysolone very slowly but this must be done under close medical supervision in direct guidance of an endocrinologist. Otherwise it can result in a life threatening complication called Adrenal Insufficiency.

Typically, I taper wysolone very slowly. I later change to hydrocortisone and do a test called ACTH stimulation to see if his 'adrenal axis' has recovered.

As his wysolone is tapered it is possible his diabetes may improve and his insulin doses may require a dose reduction. If this is not monitored closely, it will result in low glucose reactions called hypoglycemia
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shehzad Topiwala

Endocrinologist

Practicing since :2001

Answered : 1663 Questions

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What Causes Weight Gain And Swollen Face While On Wysolone?

Brief Answer: Yes Detailed Answer: Your father needs to be see in-person by an endocrinologist. This is because management of a person who has had pituitary surgery and is on steroids plus others hormones such as euthyrox and insulin, requires specialised care. Endocrinologists have advanced training in these matters. They are complex to deal with and hence expert care is necessary. For example, it appears prudent to withdraw wysolone very slowly but this must be done under close medical supervision in direct guidance of an endocrinologist. Otherwise it can result in a life threatening complication called Adrenal Insufficiency. Typically, I taper wysolone very slowly. I later change to hydrocortisone and do a test called ACTH stimulation to see if his 'adrenal axis' has recovered. As his wysolone is tapered it is possible his diabetes may improve and his insulin doses may require a dose reduction. If this is not monitored closely, it will result in low glucose reactions called hypoglycemia