Question: what could be causing my to have burning and pain in my legs at night? I have had tests done for PAD and that is not the problem. I am a diabetic (controlled last A1c 6.5) take Lisinopril 40mg, Levothyroxine 75mcg, Lipitor 10mg, Vit D3 5000 IU daily, Novalog and Levemir on a sliding scale. I also take Furosomide 20mg as needed for fluid retention. I urinate alot during the day/night because I drink at least 64oz water with lemon juice during the day. I have been following a low carb (50 carbs daily) diet for a year now losing weight. I was walking 3 miles 5x a week and doing XXXXXXX Aerobics 2x a week until about 3 mths ago when this pain began and my Thyroid went out of wack. My heart doctor started running tests for PAD and all he found was 2 places in my veins with venous insuffieciency and he prescribed Compression hose for me to wear. I usually wear them 3x a week. PAD test on arteries did not show any problems. Off and on I have taken Potassium 300 mg but not on a regular basic. I have also take a Women's +50 Multivitamin and took for a short period of time Tumeric Curcumin 500mg until 2 days ago I stopped. Can you please help me figure out what is going on with my legs.