Brief Answer:
Choline and vagus nerve stimulation decrease your anxiety.

Detailed Answer:
Hello sir,
Choline deficiency causes anxiety and choline supplements reduce the anxiety indeed. Your anxiety might be caused due to other factors like the following:
1)The following nutrients deficiency causes increased anxiety. They are :
a)magnesium
b)zinc
c)vitamin B 6
d)omega 3 fatty acids
e)choline
f)selenium
g)iron
h)vitamin D
i)Vitamins A,C,E
2)generalized anxiety disorder
3)social phobia and panic attacks.
Vagal nerve stimulation decreases agitation and calms down anxiety.There is preliminary evidence that vagus nerve stimulation is a promising add-on treatment for treatment-refractory depression, posttraumatic stress disorder, anxiety and inflammatory bowel disease.
In my opinion, vagus nerve stimulation is calming down your anxiety immediately. That rebound anxiety you get after stimulation may be due to other causes as i mentioned above.
I haven't seen any case exactly like this but seen many anxiety cases and treated too.
I don't think there is dysfunctional metabolism of acetylcholine as there would be other symptoms too like gastrointestinal and cardiovascular and parasympathetic symptoms.
Please do try the following to reduce anxiety:
1)supplementation of above mentioned vitamins and minerals through diet and tab.neurobion forte daily once for 3 months.
2)You can use SSRIs like tab.escitalopram 10 mg once daily or tab.sertraline 25mg once daily.
3) cognitive behavioural therapy is important in reducing the anxiety. So consult a clinical psychologist for therapy.
4)daily physical exercise for atleast 30 min for 5 days a week.
5)Meditation
6)progressive muscle relaxation exercises
If your anxiety doesn't subside with the above treatment, please do consult a psychiatrist.
Hope i have answered your question. Please let me know if you need any further assistance. Thank you. Take care.
Thanks.

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Brief Answer:
IBS and hyperhidrosis are due to dysfunction of autonomic nervous system.

Detailed Answer:
Hello sir, thank you for choosing healthcare magic.

Generalized hyperhidrosis may be the consequence of autonomic dysregulation, or it may develop secondary to a metabolic disorder, febrile illness, or malignancy. In its localized form, hyperhidrosis may result from a disruption followed by abnormal regeneration of sympathetic nerves.

The following are causes of hyperhidrosis :
1)neurologic and neoplastic diseases
2)Metabolic disorders or processes (eg, thyrotoxicosis, diabetes mellitus, hypoglycemia, gout, pheochromocytoma, menopause)
3)febrile illness
4) chronic alcoholism
5)various medications
6)hodgkin lymphoma
So the roots can be traced to dysfunction of autonomic nervous system or autonomic neuropathy.


Both hyperhidrosis and irritable bowel disease are due to dysregulation of autonomic nervous system,
Autonomic neuropathy occurs when there is damage to the nerves that control automatic body functions.
The nerve damage affects the messages sent between the brain and other organs and areas of the autonomic nervous system. These areas include the heart, blood vessels and sweat glands.


So, dysfunction of nerves leading to excess stimulation of the target area is the main cause of your symptoms.


Hope i have answered your question. Please let me know if you need any further assistance. Thank you. Take care.

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Brief Answer:
Treatment is the only way to ameliorate the symptoms.

Detailed Answer:
Hello sir, thank you for choosing healthcare magic. Treatment of hyperhidrosis is as follows : 1)Topical agents for hyperhidrosis therapy include topical anticholinergics, boric acid, 2-5% tannic acid solutions, resorcinol, potassium permanganate, formaldehyde (which may cause sensitization ), glutaraldehyde, and methenamine.
2)All of these agents are limited by staining, contact sensitization, irritancy, or limited effectiveness.
3)glycopyrronium tosylate topical for primary axillary hyperhidrosis in adults and children aged 9 years or older.
4)Aldehydes are used to treat the palms and soles; they are not as effective in the axillae. Glutaraldehyde solution 2% is sold as Cidex. It is not as effective but less staining. The 20-50% solution can be diluted to 10% (more effective, especially for feet, but still staining occurs).
5)Because of the limitations of other agents, Drysol (20% aluminum chloride hexahydrate in absolute anhydrous ethyl alcohol) is more commonly used as the first-line topical agent.
6)Drysol should be applied nightly on dry skin with or without occlusion until a positive result is obtained, after which the intervals between applications may be lengthened. To minimize irritation, the remainder of the medication should be washed off when the patient awakes, and the area may be neutralized with the topical application of baking soda.
7)Axillary hyperhidrosis may be treated with aluminium chloride gel
8)Systemic agents used to treat hyperhidrosis include anticholinergic medications such as propantheline bromide, glycopyrrolate, oxybutynin, and benztropine .
9)In resistant cases, iontophoresis(passing of direct current through the skin) and botulinum injection can be used.
Treatment of IBS :
Treatment depends upon your symptoms.
Mild symptoms can often be controlled by managing stress and by making changes in your diet and lifestyle. Try to:

Avoid foods that trigger your symptoms
Eat high-fiber foods
Drink plenty of fluids
Exercise regularly
Get enough sleep
For moderate to severe cases,
Fiber supplements for constipation
Antidiarrhoel medication
Laxatives for constipation
SSRIs
TCAs
Anticholinergics
Drugs specific to IBS are
1)Alosetron (Lotronex).
2)Eluxadoline (Viberzi).
3)Rifaximin (Xifaxan).
4)Lubiprostone (Amitiza).
5)Linaclotide (Linzess).
These are the treatment modalities to ameliorate the symptoms. But most of the symptoms recur and again the same treatment is to be initiated.
Hope i have answered your question. Please let me know if you need any further assistance. Thank you. Take care.

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