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What Do The Following Blood Test Reports Indicate?

Posted on Wed, 29 Jun 2016

Question: I have just seen a Hematologist/Oncologist for the first time today. My blood work seem to be all over the place, RBC Count 5.76 (H), Hemoglobin 17.0 (H), Hematocrit 52.0% (H), ABC Monocytes .60X10*3 (H)
He just diagnosed me with Polycythemia Vera does this seem correct. The CBC he just ran showed my MPV 6.9 (L), MON# .6 (H), GRA% 67.7 (H) & GRA# 6.3 (H). My blood levels are always all over the place, does any of this make sense to you because I am very confused.

Answered by Dr. Hardik Sanghvi (22 minutes later)

Brief Answer:
You should go for jak 2 mutation and repeat CBC.

Detailed Answer:
Hi, dear
I have gone through your question. I can understand your concern.

You have high rbc count, hb and hematocrit. So you have polycythemia that is final.

However you should go for confirmation about polycythemia vera. Because in some cades your polycythemia may be spurious due to other cause like dehydration.

You should go for repeat Complete blood count test and jak 2 mutation study.

Then you should take treatment accordingly.

Regular phlebotomy is the most effective treatment. Consult your doctor and take treatment accordingly.

Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic. Wish you a very good health.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Hardik Sanghvi (22 hours later)

So with Polycythemia Vera my blood levels for RBC, HB and Hematocrit can be high and then return to normal levels? I assume this explains my Dizziness, Fatigue, Rapid heart-rate, Headache, Tingling I feel in my arm's, Leg's and Extreme exhaustion I have after this episode is done? This has happened to me while driving and has scared me to death. Is this considered a life-threatening blood disorder and will it continue to progress to something worse?

Thank you

Answered by Dr. Hardik Sanghvi (12 hours later)

Brief Answer:
It can leads to some complications.

Detailed Answer:
Hi, dear
I have gone through your question. I can understand your concern.
Your symptoms of headache, tingling etc are due to polycythemia vera.

Polycythemia leads to blood thickening and it can leads to vascular complication like myocardial infarction or stroke.

To avoid this complications you should go for regular phlebotomy and drugs like aspirin or other blood thinner.

Disease progression is common but regular treatment will help you.

Consult your doctor and take treatment accordingly.

Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic. Wish you a very good health.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Hardik Sanghvi (4 days later)

Beside the diagnosis of Polycythemia Vera my most recent blood work showed problems with high iron.

My Iron was 183
Ferritin was 616.2
Iron Saturation Percent was 75.62 % saturation

What could possibly cause this and do I need to be concerned about another medical condition?

Answered by Dr. Hardik Sanghvi (13 hours later)

Brief Answer:
You should go for erytropoitin and jak 2 mutation study.

Detailed Answer:
Hi, dear
I have gone through your question. I can understand your concern.
You have high iron and ferritin level. It is very uncommon in polycythemia. In polycythemia iron level is usually low.

So you should rule out secondary polycythemia first.

So go for erythropoitin level and jak 2 mutation as I said earlier.

Then we will search for the cause of high iron.

Till that regular phlebotomy is helpful.

Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic. Wish you a very good health.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar