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What Does A High Level Of IgE Indicate?

Posted on Wed, 12 Aug 2015

Question: Hi,

My husband has a very high IGE level of 2138 but he has no symptoms of any allergies or anything wrong. He has done many tests at the hospital and they haven't found out why. He even did a bone marrow biopsy but all was clear. Should we be worried?

Answered by Dr. Drkaushal85 (1 hour later)

Brief Answer:
IgE is marker of many conditions.

Detailed Answer:
Thanks for your question on Health Care Magic.
I can understand your husband's situation and problem.
IgE is marker of many conditions like
1. Allergic disease
2. Drug reaction
3. Parasitic infection
4. Eosinophilic infiltration etc.
So please let me know
1. Is he taking any drug?
2. Is he having abdominal pain, diarrhoea etc?
3. Have you checked for stool microscopic examination?
4. Does he having eosinophilia?
Please reply me answers of above asked questions, so that I can guide you better.
I will be happy to help you further.
Wishing good health to your husband. Thanks.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Drkaushal85 (21 minutes later)

He was taking Lipitor when the first IGE test was done and at that point the level was 1900....Since then he has stopped Lipitor for two months now and the IGE levels have increased to what they are now 2138. Other than that he does not take any medication.

To be exact he has had abdominal pain (lower left side) for the past three days. The uncomfortable sensation comes and goes and he has had a loose stomach.

He has NOT had stool microspopic examination.

Do does NOT have eosinophilia....however he has had some 'positives' in antinuclear factors.

Thanks

Answered by Dr. Drkaushal85 (6 minutes later)

Brief Answer:
Possibility of parasitic infection is more in his case.

Detailed Answer:
Thanks for your follow up question on Health Care Magic.
I can understand your husband's situation and problem.
Since he is having abdominal pain and loose motions, possibility of parasitic infection is more.
So get done stool microscopic examination for ova and cyst.
Has he undergone ultrasound examination of abdomen?
Please reply me answer of above asked question, so that I can guide you better.
I will be happy to help you further.
Wishing good health to your husband. Thanks.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Drkaushal85 (5 minutes later)

Do you think it can be a parasitic infection even though the abdominal pain is happening 2 months after first noticing high ige level?

We will look into getting the stool test done.

He has NOT undergone an unltrasound of the abdomen.

Thanks

Answered by Dr. Drkaushal85 (5 minutes later)

Brief Answer:
Yes, this much delay can be seen in parasitic infection.

Detailed Answer:
Thanks for your follow up question on Health Care Magic.
I can understand your concern.
Yes, parasitic infection can show this much delay in appearance of symptoms.
So parasitic infection is a possibility in his case.
So get done ultrasound examination of abdomen and stool microscopic examination.
Please let me know if he is smoker?
I will be happy to help you further.
Wishing good health to your husband. Thanks.

Note: For further information on diet changes to reduce allergy symptoms or to boost your immunity, Ask here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar