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What Does Low Bone Density While On Depakote Indicate?

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Posted on Tue, 10 Jan 2017
Question: I an now on depakote for seizure disorder. i an finding that the last two years, my bone density is gettig lower per the density tests. I am 60 years old. Is Depakote promote bone loss? Is there something I can take for seizure disorder that will not affect bone density? I have been diagnosed with partial seizure disorder. thanks.
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Answered by Dr. Dr. Erion Spaho (42 minutes later)
Brief Answer:
Levetiracetam is an alternative.

Detailed Answer:
Hello and thanks for using HCM.

I have read your question and understand your concerns.

Depakote and other "old" antiseizure drugs may result in lowered bone density, or osteoporosis.

Keppra ( Levetiracetam ) is a good alternative in controlling partial seizures and is found not to affect bone density.

So, I think you can discuss with your Doctor about switching to Keppra.

Hope you found the answer helpful.

Kind regards.
Above answer was peer-reviewed by : Dr. Raju A.T
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Answered by
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Dr. Dr. Erion Spaho

Neurologist, Surgical

Practicing since :2004

Answered : 4502 Questions

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What Does Low Bone Density While On Depakote Indicate?

Brief Answer: Levetiracetam is an alternative. Detailed Answer: Hello and thanks for using HCM. I have read your question and understand your concerns. Depakote and other "old" antiseizure drugs may result in lowered bone density, or osteoporosis. Keppra ( Levetiracetam ) is a good alternative in controlling partial seizures and is found not to affect bone density. So, I think you can discuss with your Doctor about switching to Keppra. Hope you found the answer helpful. Kind regards.