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What Does My Blood Test Report Indicate?

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Posted on Tue, 28 Jun 2016
Question: I have just been diagnosed with hyperthyroidism I am in the UK so I believe the blood tests may be measured using different reference ranges, however if you are able to interpret these I would be grateful for comment.

My MCHC was measured at 317 (the UK ref range starts at 320) and the Mean Platelet Volume was 6.8 (UK ref range starts at 7.9). I am pu zzled by this because from what I have read the MPV would tend to be higher in hyperthyroidism?
I have had a racing heart, very irregular heart beat, dizziness and nasty headaches (I have never had headaches before in 55 yrs!).
I also had a high ACE (107) and slightly higher urea on the kidney test. My GP couldn't explain the MCHC and MPV results or the urea result.
doctor
Answered by Dr. Panagiotis Zografakis (3 hours later)
Brief Answer:
This is just hyperthyroidism

Detailed Answer:
Hello,

I've seen the report and the only result worth discussing is your thyroid status. You have hyperthyroidism and a visit to the endocrinologist is warranted.

The MCHC stands for mean corpuscular hemoglobin concentration, that is the mean concentration of hemoglobin in a red blood cell. Since you have high volume red blood cells (high MCV) and relatively low hemoglobin concentration (but normal) reflected in your MCH, it's normal for your MCHC to be lower than usual. This is not a problem when the rest of the indices are normal, so there is no reason to worry about it.

The MPV is the mean platelet volume. A platelet's volume depends on various factors. One of the most important factors is its age. A fresh platelet is larger than an old one. Also platelets rushing out of the bone barrow because the body needs more of them (when bleeding for example) are larger than usual. Low platelet volume may mean low production but if your platelet count is normal, this is nothing to worry about too.

Finally you had a high serum ACE which is expected in hyperthyroidism...

Your urea reflects your hydration status. Drinking enough water will lower your urea. Dehydration makes the urea higher. A normal creatinine level makes sure that your kidneys are functional enough, so your urea value is not worrisome either.

I hope you find my comments helpful!
You can contact me again, if you'd like any clarification or further information.

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (6 minutes later)
Just to say that was extremely helpful, thank you.
doctor
Answered by Dr. Panagiotis Zografakis (2 minutes later)
Brief Answer:
You're welcome!

Detailed Answer:
You're welcome!
Glad to help!
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
Dr.
Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3814 Questions

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What Does My Blood Test Report Indicate?

Brief Answer: This is just hyperthyroidism Detailed Answer: Hello, I've seen the report and the only result worth discussing is your thyroid status. You have hyperthyroidism and a visit to the endocrinologist is warranted. The MCHC stands for mean corpuscular hemoglobin concentration, that is the mean concentration of hemoglobin in a red blood cell. Since you have high volume red blood cells (high MCV) and relatively low hemoglobin concentration (but normal) reflected in your MCH, it's normal for your MCHC to be lower than usual. This is not a problem when the rest of the indices are normal, so there is no reason to worry about it. The MPV is the mean platelet volume. A platelet's volume depends on various factors. One of the most important factors is its age. A fresh platelet is larger than an old one. Also platelets rushing out of the bone barrow because the body needs more of them (when bleeding for example) are larger than usual. Low platelet volume may mean low production but if your platelet count is normal, this is nothing to worry about too. Finally you had a high serum ACE which is expected in hyperthyroidism... Your urea reflects your hydration status. Drinking enough water will lower your urea. Dehydration makes the urea higher. A normal creatinine level makes sure that your kidneys are functional enough, so your urea value is not worrisome either. I hope you find my comments helpful! You can contact me again, if you'd like any clarification or further information. Kind Regards!