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What Does My Blood Test Report Indicate?

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Posted on Wed, 31 May 2017
Question: My blood work was on april 14 2017 AST(sgot) 32 and ALT(sgpt) was 35
2 weeks later it was AST 42 and ALT 54. I have had a horribly itchy rash since december, we are currently testing for allergies. why the increase of the ast and alt, i am concerned. i am a 52 year old female, currently on a meal replacement diet.
doctor
Answered by Dr. Saddiq Ulabidin (1 hour later)
Brief Answer:
Need to follow Liver functions and continue allergy workup

Detailed Answer:
Hi! Welcome to HealthcareMagic! Thanks for sharing your concerns with us. We will try to help you in best way possible. First of all, it is sad to know what you had been experiencing lately.

Based on the history you have shared, regarding the first concern relating to rising liver function tests. Minor fluctuations can occur due to laboratory error or due to sample variations but even them, it can be significant trend and need to be followed further by repeating it after a week as acute hepatitis or liver pathology may present early with rising enzyme levels.

Also workup for viral serologies and lipid profile as well as ultrasound liver to look for any structural changes may be done. If these are normal, there is nothing to worry about then.

Though your drug history doesn't contain significantly hepatotoxic drug which can alter liver enzymes but avoiding analgesics can be right approach as well try to improve hydration.

You didn't mention the Bilirubin here as any rise can also cause itching as you mentioned as main complaint recently. Further evaluation of allergic rash and testing for skin allergies can be continued here. Wishing you a speedy recovery.

Hope this has answered your query, if you have any more questions, feel free to ask. Regards.
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Saddiq Ulabidin (51 minutes later)
One more thing that may have to do with something is, I am on a meal replacement diet and I have been in Ketosis, which may have something to do with the rise in AST & ALT, is that possible?
doctor
Answered by Dr. Saddiq Ulabidin (10 minutes later)
Brief Answer:
Yes it can be one reason

Detailed Answer:
Hi! Yes it can be one reason as such diets increase the metabolism and increased burden on liver but is usually reversible. Improve hydration and fluids intake. Repeating the liver function tests after two weeks and if these are still almost static then three monthly follow up would be enough if viral serologies and lipid profile are also normal. Regards.
Note: Hope the answers resolves your concerns, however for further guidance of skin related queries consult our Dermatologist.Click here to book a consultation

Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Saddiq Ulabidin

General & Family Physician

Practicing since :2011

Answered : 3941 Questions

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What Does My Blood Test Report Indicate?

Brief Answer: Need to follow Liver functions and continue allergy workup Detailed Answer: Hi! Welcome to HealthcareMagic! Thanks for sharing your concerns with us. We will try to help you in best way possible. First of all, it is sad to know what you had been experiencing lately. Based on the history you have shared, regarding the first concern relating to rising liver function tests. Minor fluctuations can occur due to laboratory error or due to sample variations but even them, it can be significant trend and need to be followed further by repeating it after a week as acute hepatitis or liver pathology may present early with rising enzyme levels. Also workup for viral serologies and lipid profile as well as ultrasound liver to look for any structural changes may be done. If these are normal, there is nothing to worry about then. Though your drug history doesn't contain significantly hepatotoxic drug which can alter liver enzymes but avoiding analgesics can be right approach as well try to improve hydration. You didn't mention the Bilirubin here as any rise can also cause itching as you mentioned as main complaint recently. Further evaluation of allergic rash and testing for skin allergies can be continued here. Wishing you a speedy recovery. Hope this has answered your query, if you have any more questions, feel free to ask. Regards.