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What Does My Lab Test Report Indicate?
Question: I have been trying to understand my results but I am so confused.. Polyclonal Gammopathy diagnosed by immunologist.
UPEP Testing
Free Kappa LT chains (0.85)Low 1.35-24.19 Free Lambda LT chains (0.05) Low 0.24-6.66 Kappa/lambda Ratio (17.00) High 2.04-10.37 Prot, 24hr (203.00)High
M-spike (not observed)
SPEP Testing
Creatinine, Serum (0.55)Low 0.57-1.00 Bun/Creatinine Ratio (33)High 8-20 Immunoglobulin A, Qn, Serum (90) Low Immunoglobulin M, Qn, Serum (254) High
M-spike (not observed)
Went to see Hematologist today and she told me that there is nothing wrong and I feel I need a second opinion.
UPEP Testing
Free Kappa LT chains (0.85)Low 1.35-24.19 Free Lambda LT chains (0.05) Low 0.24-6.66 Kappa/lambda Ratio (17.00) High 2.04-10.37 Prot, 24hr (203.00)High
M-spike (not observed)
SPEP Testing
Creatinine, Serum (0.55)Low 0.57-1.00 Bun/Creatinine Ratio (33)High 8-20 Immunoglobulin A, Qn, Serum (90) Low Immunoglobulin M, Qn, Serum (254) High
M-spike (not observed)
Went to see Hematologist today and she told me that there is nothing wrong and I feel I need a second opinion.
Brief Answer:
Investigations suggest a kidney disorder and inflammatory pathology.
Detailed Answer:
Hello,
Thanks for posting your query on HealthcareMagic.
After reviewing your investigations it is evident that there is some primary kidney disease and this is responsible for high BUN:creatinine ratio and high 24 hour protein in urine..
Thus, I suggest you to consult a nephrologist for further investigations to find out the kidney disorder.
The possibility of multiple myeloma (a neoplasm of plasma cells) is ruled out be absence of M-spike and normal levels of Ig A.
Elevated levels of Ig M is responsible for polyclonal gammopathy.
Polyclonal gammopathy can occur due to inflammation in body thus it is not possible to pin-point any condition on the basis of elevated Ig M.
Thus, it is advisable to first consult a nephrologist for kidney problem and manage it.
Thanks and take care
Dr Shailja Puri
Investigations suggest a kidney disorder and inflammatory pathology.
Detailed Answer:
Hello,
Thanks for posting your query on HealthcareMagic.
After reviewing your investigations it is evident that there is some primary kidney disease and this is responsible for high BUN:creatinine ratio and high 24 hour protein in urine..
Thus, I suggest you to consult a nephrologist for further investigations to find out the kidney disorder.
The possibility of multiple myeloma (a neoplasm of plasma cells) is ruled out be absence of M-spike and normal levels of Ig A.
Elevated levels of Ig M is responsible for polyclonal gammopathy.
Polyclonal gammopathy can occur due to inflammation in body thus it is not possible to pin-point any condition on the basis of elevated Ig M.
Thus, it is advisable to first consult a nephrologist for kidney problem and manage it.
Thanks and take care
Dr Shailja Puri
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Above answer was peer-reviewed by :
Dr. Vinay Bhardwaj
Answered by
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