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What Does Swollen Lymph Nodes In Pelvis With Prostate Cancer Indicate?
Question: Hi. I have prostate cancer found in lymph nodes of the pelvis. Why might this be an important prognostic factor?
Brief Answer:
Need some more details
Detailed Answer:
Hi
Thanks for your query.
I need a few more details to answer your query. You said that you had undergone RP, when was it done? And the negative nodes were taken out at the time of RP?
What all treatment have you received till date?
What is the current PSA?
How were these nodes detected this time, by CT scan?
What is the current bone scan report?
I will be waiting for your reply.
Regards
Need some more details
Detailed Answer:
Hi
Thanks for your query.
I need a few more details to answer your query. You said that you had undergone RP, when was it done? And the negative nodes were taken out at the time of RP?
What all treatment have you received till date?
What is the current PSA?
How were these nodes detected this time, by CT scan?
What is the current bone scan report?
I will be waiting for your reply.
Regards
Above answer was peer-reviewed by :
Dr. Raju A.T
Hi Doctor:
Thanks for replying. Here's my answers to your questions:
>>You said that you had undergone RP, when was it done?
Oct. 2009
>>And the negative nodes were taken out at the time of RP?
Yes, the nodes taken out at the time of RP--showed no evidence of disease.
>>What all treatment have you received till date?
ADT--Lupron--Intermittent, 42 sessions of salvage radiation therapy (winter, 2014).
>>What is the current PSA?
Less than 0.05
>>How were these nodes detected this time, by CT scan?
C11 Pet Scan at the Mayo Clinic, Endorectal coil MRI
>>What is the current bone scan report?
Negative for bone mets, but unspecific in certain areas.
Thanks for your help.
XXXXXX
Thanks for replying. Here's my answers to your questions:
>>You said that you had undergone RP, when was it done?
Oct. 2009
>>And the negative nodes were taken out at the time of RP?
Yes, the nodes taken out at the time of RP--showed no evidence of disease.
>>What all treatment have you received till date?
ADT--Lupron--Intermittent, 42 sessions of salvage radiation therapy (winter, 2014).
>>What is the current PSA?
Less than 0.05
>>How were these nodes detected this time, by CT scan?
C11 Pet Scan at the Mayo Clinic, Endorectal coil MRI
>>What is the current bone scan report?
Negative for bone mets, but unspecific in certain areas.
Thanks for your help.
XXXXXX
Brief Answer:
Please refer below
Detailed Answer:
Okay, now I get it. It appears that you had a rising PSA or radiological relapse while on lupron for which salvage RT was given. After that the PSA is still very low but PET and MRI has shown some small lymph nodes in the pelvis.
I feel that as long as the PSA remains low, these are not of much significance, especially as the bone scan is negative. Unless of course the nodes increase in serial scans, which becomes a prognostic factor as increasing disease burden with normal PSA may suggest transformation into an aggressive form.
Hope this answers your query. I will be available to answer further followup queries, if any.
Please refer below
Detailed Answer:
Okay, now I get it. It appears that you had a rising PSA or radiological relapse while on lupron for which salvage RT was given. After that the PSA is still very low but PET and MRI has shown some small lymph nodes in the pelvis.
I feel that as long as the PSA remains low, these are not of much significance, especially as the bone scan is negative. Unless of course the nodes increase in serial scans, which becomes a prognostic factor as increasing disease burden with normal PSA may suggest transformation into an aggressive form.
Hope this answers your query. I will be available to answer further followup queries, if any.
Above answer was peer-reviewed by :
Dr. Vinay Bhardwaj
Thank you for your answer Doctor. Before I had my radiation therapy to the pelvis, my PSA doubling time was quite rapid at 0.64/month. What type of disease does this portend? Aggressive or indolent?
Brief Answer:
Yes, this is an aggressive behavior
Detailed Answer:
However, the response to RT has been quite good and hopefully it will remained controlled for reasonable length of time.
Yes, this is an aggressive behavior
Detailed Answer:
However, the response to RT has been quite good and hopefully it will remained controlled for reasonable length of time.
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Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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