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What Does The Following Prostate Biopsy Report Indicate?
Question: A recent prostate biopsy report read as follows:
High Grade Prostatic Intraepithelial Neoplasia (HGPIN) with adjacent atypical glands: Outpouchings of PIN vs Focally Infiltrative Carcinoma.
Diagnosis was carcinoma in situ of prostate (233.4)
What does this mean and what should I do?
High Grade Prostatic Intraepithelial Neoplasia (HGPIN) with adjacent atypical glands: Outpouchings of PIN vs Focally Infiltrative Carcinoma.
Diagnosis was carcinoma in situ of prostate (233.4)
What does this mean and what should I do?
Brief Answer:
Talk to a urologist about possible surgery!
Detailed Answer:
Hi and thank you so much for this query.
I am so sorry to hear about these biopsy findings and all the disturbing thoughts this has caused you. I am however happy that this diagnosis has been made and necessary steps would be taken to help address the underlying disease condition.
The biopsy results are conclusive for prostate cancer. The best treatment for prostate cancer with no spread to other structures is surgery. However, we need to do more information to see if there are any reasons why surgery may not be the best for you at this time. Also, the medical team would try to see what benefits you would get from a possible surgery compared to alternatives measure.
In all, I will recommend that at this time you should follow up with a urologist. A comprehensive evaluation and treatment plan would be established taking into account all the obtained information and acting in your best interest.
I hope that this helps. I wish you well. Thank you for using our services and feel free to ask for more information and clarifications if needed.
Talk to a urologist about possible surgery!
Detailed Answer:
Hi and thank you so much for this query.
I am so sorry to hear about these biopsy findings and all the disturbing thoughts this has caused you. I am however happy that this diagnosis has been made and necessary steps would be taken to help address the underlying disease condition.
The biopsy results are conclusive for prostate cancer. The best treatment for prostate cancer with no spread to other structures is surgery. However, we need to do more information to see if there are any reasons why surgery may not be the best for you at this time. Also, the medical team would try to see what benefits you would get from a possible surgery compared to alternatives measure.
In all, I will recommend that at this time you should follow up with a urologist. A comprehensive evaluation and treatment plan would be established taking into account all the obtained information and acting in your best interest.
I hope that this helps. I wish you well. Thank you for using our services and feel free to ask for more information and clarifications if needed.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Is HGPIN the same as prostate cancer?What does "Outpouchings of PIN vs Focally Infiltrative Carcinoma" mean?
Brief Answer:
Grossly, this is prostate cancer!
Detailed Answer:
Hi and thanks for this follow up question.
Grossly speaking, this is cancer of the prostate.
Outpouching mean that there are pockets of these abnormal cells extending outward as opposed to infiltrative that suggests pockets of abnormal cells growing inward on the gland.
I hope this is clear enough. Let me know if there is something more you would like us to touch on at this time. I wish you well.
Grossly, this is prostate cancer!
Detailed Answer:
Hi and thanks for this follow up question.
Grossly speaking, this is cancer of the prostate.
Outpouching mean that there are pockets of these abnormal cells extending outward as opposed to infiltrative that suggests pockets of abnormal cells growing inward on the gland.
I hope this is clear enough. Let me know if there is something more you would like us to touch on at this time. I wish you well.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
What are the implications of outpouching for prognosis and treatment options?
Brief Answer:
NO implications!
Detailed Answer:
These are descriptive terms used in reporting the results.
What matters most is the grade of the tumor and whether it has move to other organs and lymph nodes or not. If it is of low grade and still confined to the prostate, that is the best in terms of prognosis.
I hope this helps. I wish you well.
NO implications!
Detailed Answer:
These are descriptive terms used in reporting the results.
What matters most is the grade of the tumor and whether it has move to other organs and lymph nodes or not. If it is of low grade and still confined to the prostate, that is the best in terms of prognosis.
I hope this helps. I wish you well.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
what are the atypical adjacent glands and what do they mean?
Brief Answer:
Atypical menas they are not normal!
Detailed Answer:
Hi and thank you so much for following up with me on this.
Atypical adjacent glands signify that these glands have features which are not normal but then they are not typical of cancer. This is often the transition stage between normal looking glands and cancer glands.
I hope this helps. Feel free to keep the discussion going if need be.
Atypical menas they are not normal!
Detailed Answer:
Hi and thank you so much for following up with me on this.
Atypical adjacent glands signify that these glands have features which are not normal but then they are not typical of cancer. This is often the transition stage between normal looking glands and cancer glands.
I hope this helps. Feel free to keep the discussion going if need be.
Note: For further queries related to kidney problems Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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