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What Does The Term "non Reactive" In A HIV 1 And 2 Test Result Indicate?

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Posted on Tue, 9 Jun 2015
Question: My penis was Sucked by a person of unknown status . I got tested with HIV 1 and 2 antibodies combo test CMIA includes p24. The tests were done at reputed lab at different time intervals( 10, 15,30,52,72,91 and at 135 day) all the tests came non reactive with 0.07 value. Would you be able to comment on my HIV status. Am I infected with HIV . What does the value and term non reactive means in this test
doctor
Answered by Dr. Swarnava Dattagupta (3 hours later)
Brief Answer:
Dont worry; you are not infected

Detailed Answer:
Hello.
Welcome to HCM.
This is Dr. Swarnava Dattagupta answering your query.

I understand your concern.
I have gone through your question and let me assure you that you are not infected with HIV. HIV 1 and 2 combined test is done to detect antibodies in blood. The antibodies can appear even till 3 months of exposure, so testing till that time is required which you have already done.
Non reactive here basically means negative. The result of 0.07 falls in the non reactive range. The cut off for positive is normally >1.0. So your result is non reactive i.e. you are not infected.
Dont worry.
Hope this was useful.
Consult me for further queries.
Regards.
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Swarnava Dattagupta (20 hours later)
Sir do i need to retest after 6 months. This incident happened on the night of 3 XXXXXXX 2015. Last I tested on 18 th may 2015 considering it as 135 day. Is my calculation for 135 day correct. I took Benadryl for a short period can it effect the results.
doctor
Answered by Dr. Swarnava Dattagupta (2 hours later)
Brief Answer:
get a final test done at 6 months if possible

Detailed Answer:
Hello again.
The chances of you being infected is very unlikely as i have already said.
In some protocols, a 6monthly test is advised to rule out any chances of infection. So if possible, you can get a final testing done. Otherwise, you dont need to. It is not mandatory. And your calculation is more or less correct.
And for your second query, benadryl wont affect test results. Dont worry.

Wish you good health.
Above answer was peer-reviewed by : Dr. Neel Kudchadkar
doctor
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Follow up: Dr. Swarnava Dattagupta (2 hours later)
Thank you doctor I am really stressed out as many doctors said 3 month antibody testing is conclusive . Out of 8 doctors I enquired 2 of them said that get tested after 6 months. This again increased my anxiety. They say that testing is conclusive between 3 to 6 months. I am really afraid doctor I am not able to control myself again and again getting tested and just reading about hiv on internet. But by your answer I am able to gain confidence. As you suggested I do not need testing I will forget this incident.
doctor
Answered by Dr. Swarnava Dattagupta (22 minutes later)
Brief Answer:
Dont worry; relax

Detailed Answer:
Hello.
Yes dont worry.
6month testing is not mandatory.
So relax.
You are not infected with HIV.

Wish you good health.
All the best.
Note: Get personalized answers to your HIV related queries You can choose to talk face to face with your doctor. Book a Video Call now.

Above answer was peer-reviewed by : Dr. Neel Kudchadkar
doctor
Answered by
Dr.
Dr. Swarnava Dattagupta

General & Family Physician

Practicing since :2013

Answered : 906 Questions

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What Does The Term "non Reactive" In A HIV 1 And 2 Test Result Indicate?

Brief Answer: Dont worry; you are not infected Detailed Answer: Hello. Welcome to HCM. This is Dr. Swarnava Dattagupta answering your query. I understand your concern. I have gone through your question and let me assure you that you are not infected with HIV. HIV 1 and 2 combined test is done to detect antibodies in blood. The antibodies can appear even till 3 months of exposure, so testing till that time is required which you have already done. Non reactive here basically means negative. The result of 0.07 falls in the non reactive range. The cut off for positive is normally >1.0. So your result is non reactive i.e. you are not infected. Dont worry. Hope this was useful. Consult me for further queries. Regards.