What Does These Abnormal Liver Test Values Indicate?

Posted on Fri, 4 Apr 2014

Question: Hi Dr My Billirurbin Total is in between 1.7 to 1.9 , SGOT 24-28; SGPT 86 to 64 from the last one year , i am not taking alcohol, if this is problematic? please advice me how i got normal values

Answered by Dr. Saumya Mittal (40 minutes later)

Brief Answer: I think this is continued infection Detailed Answer: Hi Mr XXXXX I am Dr Saumya Mittal And I am going to try and help you with your query and your doubts I have read your query. The fact remain that you have had hepatitis B infection. HBsAg is a test that marks the acute stage of the infection. From the silence about the subject in the query, I am also assuming that you have not had antiviral therapy for hepatitis B. The other fact remains that the report suggests that the virus is probably remaining in the liver and that it has not completely gone. The negative test of HBsAg just suggests that the acute infection is over. The liver function test reports suggest that the infection is proceeding. I would suggest to a patient I was treating to consider taking antiviral therapy. It is usually needed for at least 6 months. Thereafter the continuity of the therapy depends on how you respond to the therapy. Of course this would need a gastroenterologist experienced in the administration of these medicines. There would be certain tests needed before starting the therapy, during the therapy and a few after the course is over. I hope that helps. Do feel free to ask any related further query or doubt. Best of luck Dr Mittal

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Saumya Mittal (13 hours later)

Yes i am not taking any anti viral therapy, because in the initial time ie April 13 viral load is < 3.8 and i consult to a dr and he not advice to take any antiviral. further more the results Hepatitis B e antibody found -ve at April 13 as well as September 13. Still you think that my liver has infection? please suggest me some mediation also if u feel.

Answered by Dr. Saumya Mittal (55 minutes later)

Brief Answer: Further tests required Detailed Answer: I think you should check the HBV DNA PCR (Quantitative) and HBV Viral load again. The tests may tell us if the hepatitis virus are proliferating, especially in the view of HBe negative status. meanwhile have a prescription filled for ursodeoxycholic acid. Also requesting to upload the report of LFT Antiviral therapy can be started only when the replication is started Looking forward to your response Best of luck Dr Saumya Mittal

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Saumya Mittal (24 minutes later)

here the LFT results: Date 20-04-13 SGOT 24; SGPT 79; Alkaline Phosphates 227; Bilirubin Total 1.8, Direct 0.3, Indirect 1.5; Albumin 5; Globulin 3 Date 02-09-13 SGOT 36; SGPT 86; Alkaline Phosphates 226; Bilirubin Total 1.5, Direct 0.7, Indirect 0.8; Albumin 4.8; Globulin 2.5 Date 23-12-13 SGOT 38; SGPT 59; Alkaline Phosphates 264; Bilirubin Total 1.2, Direct 0.3, Indirect 0.9; Albumin 5; Globulin 2.9 Date 15-03-14 SGOT 28; SGPT 64; Alkaline Phosphates 218; Bilirubin Total 1.9, Direct 0.8, Indirect 1.1; Albumin 4.9; Globulin 2.4 men time on date 08-10-13 Lipid profile also performed report Serum Appearance; Clear; S Cholestrol 196; S triglyceride 118; HDL calosterol 46; LDL 126 also please advice me how to take the above medication.

Answered by Dr. Saumya Mittal (4 hours later)

Brief Answer: tests as a precaution Detailed Answer: that was a very good idea to enter all the LFT reports. I think now we know that the levels of liver enzymes and bilirubin are largely constant. So, I would suggest you have the tests just to be sure. I dont think it is something very serious. The tablet I mentioned can be taken twice a day. But since I am not aware of the whole history, as was made obvious with those reports, I would suggest you meet your gastroenterologist before starting the medicine. Mild rise of enzymes can also be in view of high cholesterol levels. Your last tests were borderline, so I would suggest repeating those as well. Please do let me know the reports and any further query you may have Best of luck Dr Mittal

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar