
What Does This FNAC Report Indicate?

Question: I am 53 years old recently menopausal, with fibrocystic breasts. Recently on my annual mammogram an oval well defined lesion was seen with cluster of microcalcifications in it. This lesion was there years. Before but never questioned and dis not have calcifications. Doctor did a stereotactic FNAC as nothing was seen on ultrasound and she suspected fibrocystic area/change. The FNAC report is as follows:
The aspirates show approximately seven groups and clusters of benign epithelial and myoepithelial cells. Small fragments of adipose tissue and calcifications are also present.
Result: benign epithelial leaion C2
The report is not specific at all and although the breast surgeon said its fibrocystic change. shouldn't apocrine and foam cells be present?
What could the pathologist mean by benign epithelial leaion based on this report ?
The aspirates show approximately seven groups and clusters of benign epithelial and myoepithelial cells. Small fragments of adipose tissue and calcifications are also present.
Result: benign epithelial leaion C2
The report is not specific at all and although the breast surgeon said its fibrocystic change. shouldn't apocrine and foam cells be present?
What could the pathologist mean by benign epithelial leaion based on this report ?
Brief Answer:
Hello. Apocrine cells may not be there
Detailed Answer:
Hello dear. I have gone through the details. So the biopsy report is consistent with what we call fibrocystic changes and there is actually nothing to fear. With time and after menopause, the estrogenic stimulus is lost and the glands shows involution and regression and hence apocrine and foam crlls may not be seen. This can also be termed as aberrations of normal development and involutions. This is perfectly ok. Any breast lesion which is not a cancer is termed as benign epithelial lesion and hence the pathologist used this term. Hope it is clear.
Thanks and regards
Feel free to ask further
Hello. Apocrine cells may not be there
Detailed Answer:
Hello dear. I have gone through the details. So the biopsy report is consistent with what we call fibrocystic changes and there is actually nothing to fear. With time and after menopause, the estrogenic stimulus is lost and the glands shows involution and regression and hence apocrine and foam crlls may not be seen. This can also be termed as aberrations of normal development and involutions. This is perfectly ok. Any breast lesion which is not a cancer is termed as benign epithelial lesion and hence the pathologist used this term. Hope it is clear.
Thanks and regards
Feel free to ask further
Above answer was peer-reviewed by :
Dr. Raju A.T


Thank you doctor for the detailed response. The doctor said the FNAC is accurate in this case as the sample shows calcifications so they got the right spot and there is no need for core biopsy. Would you agree that the FNAC would be sensitive enough in this case ?
So it is possible for fibrocyatic area not to show any foam or apocrine cells ? is it possible for this lesion to be a fibroadenoma or is the pathology for that different than my report?
So it is possible for fibrocyatic area not to show any foam or apocrine cells ? is it possible for this lesion to be a fibroadenoma or is the pathology for that different than my report?
Brief Answer:
Hello. The fnac is ok
Detailed Answer:
Hello dear. So the fnac is accurate and all the parameters mentioned are also consistent with your age and a benign lesion. It is not gibroadenoma but only fibrocystic changes. You need not to worry. Biopsy is not required.
Thanks and regards
Hello. The fnac is ok
Detailed Answer:
Hello dear. So the fnac is accurate and all the parameters mentioned are also consistent with your age and a benign lesion. It is not gibroadenoma but only fibrocystic changes. You need not to worry. Biopsy is not required.
Thanks and regards
Above answer was peer-reviewed by :
Dr. Yogesh D


Thank you for your concern, i am not worried, i would just like to know more details.
The breast FNAC reports i have seen are usually specific, why would my report be non-specific and not mentioning fibrocystic change ?
Benign epithelial lesion can be any benign disease not necessairly fibrocystic, so why wouldn't my report be more specific as to what this lesion/calcifications are due to?
The breast FNAC reports i have seen are usually specific, why would my report be non-specific and not mentioning fibrocystic change ?
Benign epithelial lesion can be any benign disease not necessairly fibrocystic, so why wouldn't my report be more specific as to what this lesion/calcifications are due to?
Brief Answer:
Hello. It is just a way of reporting
Detailed Answer:
Hello dear. It is just a way of reporting the pathology and can ary from institutions to another institution and bwtween different dkctoray. But final conclusion is same, either benign or malignant lesion. Report is acceptable.
Thanks and regards
Hello. It is just a way of reporting
Detailed Answer:
Hello dear. It is just a way of reporting the pathology and can ary from institutions to another institution and bwtween different dkctoray. But final conclusion is same, either benign or malignant lesion. Report is acceptable.
Thanks and regards
Above answer was peer-reviewed by :
Dr. Prasad


Thanks doctor. One last question, in what percentage of fibrocystic changes apocrine and foam cells seen ?
My mother has been in menopause for less than a year, is it enough for loss of apocrine and foam cells in her fibrocystic breast tissue ?
My mother has been in menopause for less than a year, is it enough for loss of apocrine and foam cells in her fibrocystic breast tissue ?
Brief Answer:
Hello. Most of the cases in menopause dont show apocrine
Detailed Answer:
Hello dear. Exact percentage is not known as this is not relevant after menopause, but mostly dont show after menopause.
Thanks and regards
Hello. Most of the cases in menopause dont show apocrine
Detailed Answer:
Hello dear. Exact percentage is not known as this is not relevant after menopause, but mostly dont show after menopause.
Thanks and regards
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Above answer was peer-reviewed by :
Dr. Prasad

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