Question: Dear Doctor,

I communicated with you already in another query regarding my hiv test results which i took 14 months after risky exposure,you have explained me well, but still I have few doubts about my HIV-1 RNA PCR QUALITATIVE result.

Please see attached reports for your review, especially have a look on hiv1 rna pcr qualitative result.

1.My HIV-1 PCR rna qualitative result is ' NOT DETCTABLE'( I see from interpretation part 'NOT DETECTABLE' means absence of hiv-1 infection or sample is having less than 20copies),what does mean POSITIVE or NEGATIVE?

2.I see many other labs are mentioning 'NOT DETECTED' for negative hiv rna pcr qualtive results,why this lab has mentioned 'NOT DETECTABLE' instead of 'NOT DETECTED'?(pls note my hiv-2 rna pcr qualitative result mentioned-NOT DETECTED) anything is there technically behind on this 'NOT DETECTABLE' result?

3.Even if I take a child(unexposed to HIV) to this lab for this hiv-1 rna pcr qualitative test , what result i can expect whether 'NOT DETECTABLE' or 'NOT DETECTED'?

4.I used to see NOT DETECTABLE result for HIV-1 RNA PCR QUANITATIVE test, not on QULAITATIVE test (as per my knowledge). do you see any other labs are mentioning 'NOT DETECTABLE' for qualitative hiv-1 rna pcr test result if patient is hiv negative status?

5.there is any difference between this two words 'NOT DETECTABLE' and 'NOT DETECTED' on HIV-1 pcr rna qualitive test ?

6. Finally based on my report please let me know my HIV-1 RNA PCR Qualitative test indicates POSITIVE or NEGATIVE result?

Please doctor explain me in details regarding my hiv-1 rna pcr qualitative result.

Thank you.

Thanks Dr for your valuable answers,

Now I am clear about my pcr rna qualitative test result which indicates NEGATIVE.

I have been taking so many hiv tests Since my exposure, my exposure exactly 16 months before from now, all my tests were negative results except one rapid hiv test which I took in east XXXXXXX

I am living in east XXXXXXX after 12 months from exposure ,I went for rapid hiv test ,I was in lab when lab technician was performing Determine rapid antibody test, after putting my blood on strip he was looking for buffer solution, by mistake he used UNIGOLD (different brand) chase buffer solution on Determine strip, the result was weakly positive(slightly visible patient line and clear visible control line), I told him about different brand buffer he used, immediately the same time he repeated the tests( determine and Unigold) with right buffer solutions, i got negative results.

1.here I am worrying about two things ,i have persistent symptoms till today after 3 months from exposure, like slightly white coating tongue and acne type rashes on my back, which i never had before my exposure.

2.my second concern about weakly positive result which I got, there is any chance due to different brand buffer I got that result?

2.Generally can lab use one brand buffer on different brand strip? if yes is it bring accurate result?

my last tests as below,

14months after exposure - western blot,P24antigen,HIV duo- all non reactive
hiv 1&2 PCR rna qualitaiitive- all negative.
all other stds were neagative(syphilis,HBV,HCV,hsv1&2)
15months after exposure- HIV duo-negative,
HIV-1 rna quantitative- Target not detected.
16months after exposure- HIV rapid test (sd bioline)- negative.

4.Doctor after going through my complete history, symptoms currently which i have and test results(including weakly positive) in different intervals, can you conclude my hiv status?

5. I am newly married two months before, without any doubt about hiv, can i have unprotected sex with my life?

6.Do i need to repeat my hiv tests in future?

Thanks doctor for your time.

Dear Doctor,

Many thanks for your answers.

You were clearly explained about my doubts,

I see so many information's in internet regarding hiv testing, but I realize now that specialists like you only can provide right information based on exposure, history and results.

1.after taking so many advance hiv tests ,Can I ignore my false positive rapid test?(due to different buffer used or something else).

2.you have advised me to inquire about false positive rapid test result with microbiologist or lab expert , is it necessary?

3.Do you think this is enough time (14months) to detect antibodies,antigen and virus?here there is any remote chance for my hiv neagative status to change positive in future without any new exposure?

4.pls may I know normal cd4/cd ratio for hiv negative person, male?

5.Now I am taking below medicines for acne treatment for two months,

Doxiem(Doxycycline hyclate),
Allerpar(chlorpheniramine malete,calcium gluonate with vitamin C)
Biona-E(Biotin,N-acetyl cysteine,vitamin and minerals)
Clindamycin phosphate topical solution applying on body

Can I plan for child while i am taking above mentioned medicines? they will alter anything in my sperm? this medicines will affect baby health if my wife gets pregnancy on this time?

Thank you.

Thanks doctor for your answers,

I am closing the discussion here, Finally I need to know from you,

1.there is any chance my hiv negative status will change in future without any new exposure?

2.My hiv results are 100% conclusive? can I plan for a child without hiv fear?

3.do I need to take any hiv tests in future?

Thanks doctor for your answers and time.