Question: Hi Dr XXXXXXX

I am writing again with similar sinus issues as before. I ended up doing the sinus surgery January 6th and have never felt completely better since. I was cultured right before the surgery, which came back with an overgrowth of citrobacter ferundii (the same infection from a year prior). I held off on antibiotics. I have been back to the ENT several times after surgery and each time I have yellow/green mucous that needs to be cleaned. I have asked him to culture it 2 more times and each time it has returned with no growth. The ENT prescribed an antifungal, levoquin, and a steroid in a nebulizer to treat the infection. I don't do well on levoquin. So my question is... would you treat the infection without a positive culture. And the color of the mucous is golden rod yellow, which I thought (and my ENT mentioned) might be staph. I know sinus staph as well as citrobacter are treated with doxycycline (the original cultures both grew sensitivity to levoquin, cipro, bactrim, and doxycycline). I'm allergic to bactrim, cipro and levoquin gave me bad reactions, and I have taken two courses of Doxycycline with no improvements. Should I try the doxycycline again now that my sinuses are draining or should I just give the Levoquin a shot? I was told the the absorption rate of these medications is very low.