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What Is The Cause And Treatment For Urticaria And Angioedema?

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Posted on Sat, 12 Jul 2014
Question: I gradually went off the beta blocker and the amlotophine bensalate and am now on Lisinopril w/fluid additive. Still seem to have all the same allergeric reactions, itchy skin, creeping hair, burning skin and overall just feeling bad. Seems like I feel worse after eating. Sugar checks okay, clesterol is 250, not taking meds for it, holding off everything trying to figure out what I am have allergeric reaction too. Seems like I have something wrong in sinus area, after having all the high blood pressure attacks while I was taking clonodine. Please advise!
doctor
Answered by Dr. Hardik Pitroda (52 minutes later)
Brief Answer:
change antihypertensive, food diary

Detailed Answer:
Hello,
Thank you for posting on HCM.
I can appreciate your concern regarding the skin condition.

It seems you are having attacks of urticaria and angioedema.
Its an allergic manifestation of skin, where an allergen leads to release of certain substances from your blood, leading to itchy skin rash and swelling over soft tissues.

From your history it seems you have either food-induced urticaria or drug induced.

Anti-hypertensive drugs are very notorious for causing urticaria. Since you have already stopped beta blockers and amlodipine which can definitely cause such reaction, but the current medication Lisinopril is an ACE inhibiot which actually is major culprit for urticaria.

I suggest you to have through consult with your dermatologist regarding this issue.

In my patients of urticaria, in usually start with thorough history and investigations. I also suggest some specific tests like patch test, food prick test, IgE antibody levels etc. in selected cases.

Try to maintain a food diary where you list every product you consumed in prior 12 hours before the development of rash. Regular maintenance of such notes will help us in guiding towards the offending food allergen.

Also, check with your doctor regarding the safer substitute for hypertension, I think other feasible class of drugs would be Angiotensin-receptor blockers(ARBs).

As for treatment part, best would be the avoidance of allergen as far as possible. Try to eliminate possible triggering foods from diet. I would also advise you various anti-histaminics for long duration( atleast 3 months) with or without oral corticosteroids. For non- responding cases there are many other drugs like dapsone, cyclosporine, montelukast, omalizumab etc which can be used in certain selected cases.

Hope this will help you in resolving your query.
Let me know if there is anything more you would like to know from my side.
Kindly drop your valuable review at the following link:http://doctor.healthcaremagic.com/doctors/dr-hardik-pitroda/67169

Thank you and take care,
Dr Hardik Pitroda
M.D Dermatology
Note: For further information on diet changes to reduce allergy symptoms or to boost your immunity, Ask here.

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
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Answered by
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Dr. Hardik Pitroda

Dermatologist

Practicing since :2010

Answered : 1489 Questions

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What Is The Cause And Treatment For Urticaria And Angioedema?

Brief Answer: change antihypertensive, food diary Detailed Answer: Hello, Thank you for posting on HCM. I can appreciate your concern regarding the skin condition. It seems you are having attacks of urticaria and angioedema. Its an allergic manifestation of skin, where an allergen leads to release of certain substances from your blood, leading to itchy skin rash and swelling over soft tissues. From your history it seems you have either food-induced urticaria or drug induced. Anti-hypertensive drugs are very notorious for causing urticaria. Since you have already stopped beta blockers and amlodipine which can definitely cause such reaction, but the current medication Lisinopril is an ACE inhibiot which actually is major culprit for urticaria. I suggest you to have through consult with your dermatologist regarding this issue. In my patients of urticaria, in usually start with thorough history and investigations. I also suggest some specific tests like patch test, food prick test, IgE antibody levels etc. in selected cases. Try to maintain a food diary where you list every product you consumed in prior 12 hours before the development of rash. Regular maintenance of such notes will help us in guiding towards the offending food allergen. Also, check with your doctor regarding the safer substitute for hypertension, I think other feasible class of drugs would be Angiotensin-receptor blockers(ARBs). As for treatment part, best would be the avoidance of allergen as far as possible. Try to eliminate possible triggering foods from diet. I would also advise you various anti-histaminics for long duration( atleast 3 months) with or without oral corticosteroids. For non- responding cases there are many other drugs like dapsone, cyclosporine, montelukast, omalizumab etc which can be used in certain selected cases. Hope this will help you in resolving your query. Let me know if there is anything more you would like to know from my side. Kindly drop your valuable review at the following link:http://doctor.healthcaremagic.com/doctors/dr-hardik-pitroda/67169 Thank you and take care, Dr Hardik Pitroda M.D Dermatology