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What Is The Effect Of Candesartan On Heart Attack And Stroke?

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Posted on Wed, 28 Jan 2015
Question: Is there a reputable study to show that taking candesartan actually reduces the incidence of heart attack and stroke?
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Answered by Dr. Anshul Varshney (1 hour later)
Brief Answer:
There are many studies and trials.

Detailed Answer:
Welcome To HCM. I am Dr Anshul Varshney.
I understand your concern.
There are many trials which are reputed likf SCOPE trial , SCAST trial which show that there are mortality and morbidity benefits and reduction in incidence of stroke and myocardial infarction in patients being treated with Angiotensin Receptor Blockers (ARB's) like Candesartan.
ACE inhibitors and ARB's are well known for this.
If you have any further query, please ask me.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Anshul Varshney (1 hour later)
What percentage reduction was achieved in the incidence of heart attack and stroke and how many individuals in the trials?

In the side effects of candesartan, is there an effect on the blood vessels or nerves of the feet?
doctor
Answered by Dr. Anshul Varshney (5 hours later)
Brief Answer:
That Varies in different studies.

Detailed Answer:
Dear Friend.
This would be difficult for me to answer because this varies from studies to studies. Moreover there are many risk factors and criterias which are taken into consideration.
You can refer to the articles for exact details. If we talk about clinical practice we often prescribe ARB's for the purpose.
ARB's don't have a significant effect in neuropathy best to my knowledge.
But apart from heart and stroke, ARB's role is well established in patients with proteinuria due to nephropathy.
I hope it helps .
Stay Healthy.
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Answered by
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Dr. Anshul Varshney

Internal Medicine Specialist

Practicing since :2009

Answered : 3071 Questions

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What Is The Effect Of Candesartan On Heart Attack And Stroke?

Brief Answer: There are many studies and trials. Detailed Answer: Welcome To HCM. I am Dr Anshul Varshney. I understand your concern. There are many trials which are reputed likf SCOPE trial , SCAST trial which show that there are mortality and morbidity benefits and reduction in incidence of stroke and myocardial infarction in patients being treated with Angiotensin Receptor Blockers (ARB's) like Candesartan. ACE inhibitors and ARB's are well known for this. If you have any further query, please ask me.