What Is The Most Effective Treatment For Follicular Lymphoma?

Posted on Mon, 9 Oct 2023

Question: Statistically speaking, what is the most effective INITIAL treatment for
follicular lymphoma after the spreading starts toward the organs.
I am finishing up year 6, and progression is happening.

Answered by Dr. Dr. Esmeralda Sera (3 hours later)

Brief Answer:
FL

Detailed Answer:
Hello and thank you for asking

Your doctor will suggest you the right treatment.

Some of the treatment that can be used are

Rituximab 375 mg/m2 IV weekly for 4week

Any rituximab chemotherapy regimen described in the first-line treatment setting that was not used before

Regards

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Dr. Esmeralda Sera (14 hours later)

Ha Ha! Seems from your answer, no rituximab/chemo regimen has yet to be successful - hence the 'try something new' is the take away. It's the classic 'kick the can down the road' therapy - a rather futile effort to eek out a couple, or few more years - filled with discomfort and unpleasantness to boot.

Any other promising therapies on the horizon - or in clinical trials?

Answered by Dr. Dr. Esmeralda Sera (43 minutes later)

Brief Answer:
FL

Detailed Answer:
Hello

Retuximab its good choice

Idelalisib 150 mg PO BID (PI3K) its XXXXXXX inhibitor that has been granted accelerated approval by the US Food and Drug Administration (FDA) (confirmatory clinical trials in progress) for relapsed FL

Above answer was peer-reviewed by : Dr. Nagamani Ng

Follow up: Dr. Dr. Esmeralda Sera (5 hours later)

In the 'standard' complete blood count, what are the most important tests results that are flagged 'low' or 'high'? In my latest result of 'whole blood' the out of range tests are as follows: All others are normal, of course.
WBC low @ 4.7
LY# low @ 1.0
RBC low @ 4.65
--------------
EO% high @ 3.2
BA% high @ 1.1
MCH high @ 32.3
MPV high @ 10.7

Answered by Dr. Dr. Esmeralda Sera (3 minutes later)

Brief Answer:
FL

Detailed Answer:
Hi

In my opinion your exams results aren’t to far from normal range ,due to the fact that you have FL

Above answer was peer-reviewed by : Dr. Prasad

Answered by Dr. Dr. Esmeralda Sera (50 minutes later)

Brief Answer:
FL

Detailed Answer:
Hi

More than 30 per cent higher or lower of normal values we will consider risks for the patient

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Dr. Esmeralda Sera (4 minutes later)

Thank you for your replies .. (I forget I'm not addressing a machine!)

Anyway, at what general %, high or low in any catagory, should the 'panic button' (concern) come into play? Or, just more than 5 lows and highs?

Answered by Dr. Dr. Esmeralda Sera (22 hours later)

Brief Answer:
FL

Detailed Answer:
Hi again

That is very healthy lifestyle .You should continue the same wey and for sure you should stay positive

Above answer was peer-reviewed by : Dr. Raju A.T

Follow up: Dr. Dr. Esmeralda Sera (8 minutes later)

Given that you might have a pretty good outline of where I am in this saga, what would you do to (albeit you are female) going forward? 'Watchful waiting' is the current mode.

Not sure if I mentioned, I do a 30 minute exercise routine 5 days a week - 'circuit' weightlifting for upper and lower body strength at a steady, continuous pace.
I eat greens/ avocados/nuts/ eggs/carrots, etc. plus whey protein and a total nutrient powder mixed with water twice daily and 3 fish oil capsules daily.

Is there anything else? (I do have a positive attitude!)